Cellular events of acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates

Cellular events of acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates

Here, Fahlberg et al. describe the cellular immune response during acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates. The study identifies associations of monocytes and macrophage subtypes in lungs with disease outcome, IL-6 and IL-10 ratio in plasma, and viral repli...

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Autores principales: M. D. Fahlberg, R. V. Blair, L. A. Doyle-Meyers, C. C. Midkiff, G. Zenere, K. E. Russell-Lodrigue, C. J. Monjure, E. H. Haupt, T. P. Penney, G. Lehmicke, B. M. Threeton, N. Golden, P. K. Datta, C. J. Roy, R. P. Bohm, N. J. Maness, T. Fischer, J. Rappaport, M. Vaccari
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ed379c7b9e49434d81343f5e0569e2da
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Sumario:Here, Fahlberg et al. describe the cellular immune response during acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates. The study identifies associations of monocytes and macrophage subtypes in lungs with disease outcome, IL-6 and IL-10 ratio in plasma, and viral replication in bronchial brushes.

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