THE EFFICIENCY OF TOLERANT (PASSIVE) ADAPTATION UNDER THE CONDITIONS OF EXPERIMENTAL POLYTRAUMA

The model of multiple skeletal injuries was reproduced in two groups. 22 animals of the 1st group had stabilization of the right forearm bones and left shin with spoke external fixation device of 2 subsystems with followed osteotomy of the bones of respective segment in the middle third under genera...

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Autores principales:	M. L. Lebed, M. G. Kirpichenko, S. N. Bocharov, V. V. Gumanenko
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2013
Materias:	multiple skeletal injuries tolerance mortality adrenaline dexamethasone Science Q
Acceso en línea:	https://doaj.org/article/ed3989f8f53145b88f2ca8f31d519a8c
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spelling	oai:doaj.org-article:ed3989f8f53145b88f2ca8f31d519a8c2021-11-23T06:14:26ZTHE EFFICIENCY OF TOLERANT (PASSIVE) ADAPTATION UNDER THE CONDITIONS OF EXPERIMENTAL POLYTRAUMA2541-94202587-9596https://doaj.org/article/ed3989f8f53145b88f2ca8f31d519a8c2013-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1465https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The model of multiple skeletal injuries was reproduced in two groups. 22 animals of the 1st group had stabilization of the right forearm bones and left shin with spoke external fixation device of 2 subsystems with followed osteotomy of the bones of respective segment in the middle third under general anesthesia. During the experiment the injection of dexamethasone and adrenaline during the first twenty-four hours after multiple skeletal injuries prevented the reduce the intensity of the metabolic processes, that was proved by close to initial values of oxygen consumption and carbon dioxide emissions. But to the third day there was no any difference in the metabolic activity in rabbits having and not having adrenaline and dexamethasone. The animals had adrenaline and dexamethasone turned to be in more severe clinical situation. As a result of «normal» intensity of metabolic processes in rabbits during the near time period after trauma there was decrease of survival from 45,5 % to 7,7 %.M. L. LebedM. G. KirpichenkoS. N. BocharovV. V. GumanenkoScientific Сentre for Family Health and Human Reproduction Problemsarticlemultiple skeletal injuriestolerancemortalityadrenalinedexamethasoneScienceQRUActa Biomedica Scientifica, Vol 0, Iss 2(2), Pp 148-151 (2013)
institution	DOAJ
collection	DOAJ
language	RU
topic	multiple skeletal injuries tolerance mortality adrenaline dexamethasone Science Q
spellingShingle	multiple skeletal injuries tolerance mortality adrenaline dexamethasone Science Q M. L. Lebed M. G. Kirpichenko S. N. Bocharov V. V. Gumanenko THE EFFICIENCY OF TOLERANT (PASSIVE) ADAPTATION UNDER THE CONDITIONS OF EXPERIMENTAL POLYTRAUMA
description	The model of multiple skeletal injuries was reproduced in two groups. 22 animals of the 1st group had stabilization of the right forearm bones and left shin with spoke external fixation device of 2 subsystems with followed osteotomy of the bones of respective segment in the middle third under general anesthesia. During the experiment the injection of dexamethasone and adrenaline during the first twenty-four hours after multiple skeletal injuries prevented the reduce the intensity of the metabolic processes, that was proved by close to initial values of oxygen consumption and carbon dioxide emissions. But to the third day there was no any difference in the metabolic activity in rabbits having and not having adrenaline and dexamethasone. The animals had adrenaline and dexamethasone turned to be in more severe clinical situation. As a result of «normal» intensity of metabolic processes in rabbits during the near time period after trauma there was decrease of survival from 45,5 % to 7,7 %.
format	article
author	M. L. Lebed M. G. Kirpichenko S. N. Bocharov V. V. Gumanenko
author_facet	M. L. Lebed M. G. Kirpichenko S. N. Bocharov V. V. Gumanenko
author_sort	M. L. Lebed
title	THE EFFICIENCY OF TOLERANT (PASSIVE) ADAPTATION UNDER THE CONDITIONS OF EXPERIMENTAL POLYTRAUMA
title_short	THE EFFICIENCY OF TOLERANT (PASSIVE) ADAPTATION UNDER THE CONDITIONS OF EXPERIMENTAL POLYTRAUMA
title_full	THE EFFICIENCY OF TOLERANT (PASSIVE) ADAPTATION UNDER THE CONDITIONS OF EXPERIMENTAL POLYTRAUMA
title_fullStr	THE EFFICIENCY OF TOLERANT (PASSIVE) ADAPTATION UNDER THE CONDITIONS OF EXPERIMENTAL POLYTRAUMA
title_full_unstemmed	THE EFFICIENCY OF TOLERANT (PASSIVE) ADAPTATION UNDER THE CONDITIONS OF EXPERIMENTAL POLYTRAUMA
title_sort	efficiency of tolerant (passive) adaptation under the conditions of experimental polytrauma
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2013
url	https://doaj.org/article/ed3989f8f53145b88f2ca8f31d519a8c
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THE EFFICIENCY OF TOLERANT (PASSIVE) ADAPTATION UNDER THE CONDITIONS OF EXPERIMENTAL POLYTRAUMA

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