Laparoscopic versus opengastric surgery for the treatment of pathological T1N0M0 gastric cancer in elderly patients: a matched study

Abstract The aim of this study was to compare the outcomes of laparoscopic surgery (LAP) and open gastric surgery (OP) in early gastric cancer patients aged ≥70 years.We conducted a retrospectively analysis among patientswith pathological T1N0M0 gastric cancer,who underwent LAP or OP between January...

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Autores principales:	Haiyan Pan, Tao Li, Zhigang Huang, Haibing Yu, Danli Kong, Yuanlin Ding, Congcong Pan, Yugang Jiang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ed3d5c0ba5b4496daebaf3a393674aa4
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spelling	oai:doaj.org-article:ed3d5c0ba5b4496daebaf3a393674aa42021-12-02T16:06:35ZLaparoscopic versus opengastric surgery for the treatment of pathological T1N0M0 gastric cancer in elderly patients: a matched study10.1038/s41598-017-02182-52045-2322https://doaj.org/article/ed3d5c0ba5b4496daebaf3a393674aa42017-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-02182-5https://doaj.org/toc/2045-2322Abstract The aim of this study was to compare the outcomes of laparoscopic surgery (LAP) and open gastric surgery (OP) in early gastric cancer patients aged ≥70 years.We conducted a retrospectively analysis among patientswith pathological T1N0M0 gastric cancer,who underwent LAP or OP between January 1, 2001 and December 31, 2008. We identified a well-balanced cohort of 2,360 patients (1180 patients in each group). LAP has been shown to offer a superior perioperative results to OP, including lower blood loss, shorter time to oral intake, walk and bowel function recovery, shorter time of hospital stay, and less blood transfusion required. However, the intraoperative and postoperative complications, local recurrence, and metastasis didn’t show statistically significant differences between groups. The 5-year overall survival (OS), disease-free survival (DFS), and cancer-specific survival (CSS) were 60.1% vs.63.2%, 80.8% vs. 83.3%, and 87.6% vs. 89.5% in the LAP group and OP group, respectively. The hazard ratios (HR) for OS, DFS, and CSS were 1.09(95% confidence interval [CI]: 0.95–1.25; P = 0.215), 1.03(95% CI: 0.91–1.18; P = 0.636), and 1.07 (95% CI: 0.88–1.30; P = 0.484), respectively, compared LAP group with OP group. In conclusion, LAP is an acceptable alternative to OP in elderly patients with early gastric cancer.Haiyan PanTao LiZhigang HuangHaibing YuDanli KongYuanlin DingCongcong PanYugang JiangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Haiyan Pan Tao Li Zhigang Huang Haibing Yu Danli Kong Yuanlin Ding Congcong Pan Yugang Jiang Laparoscopic versus opengastric surgery for the treatment of pathological T1N0M0 gastric cancer in elderly patients: a matched study
description	Abstract The aim of this study was to compare the outcomes of laparoscopic surgery (LAP) and open gastric surgery (OP) in early gastric cancer patients aged ≥70 years.We conducted a retrospectively analysis among patientswith pathological T1N0M0 gastric cancer,who underwent LAP or OP between January 1, 2001 and December 31, 2008. We identified a well-balanced cohort of 2,360 patients (1180 patients in each group). LAP has been shown to offer a superior perioperative results to OP, including lower blood loss, shorter time to oral intake, walk and bowel function recovery, shorter time of hospital stay, and less blood transfusion required. However, the intraoperative and postoperative complications, local recurrence, and metastasis didn’t show statistically significant differences between groups. The 5-year overall survival (OS), disease-free survival (DFS), and cancer-specific survival (CSS) were 60.1% vs.63.2%, 80.8% vs. 83.3%, and 87.6% vs. 89.5% in the LAP group and OP group, respectively. The hazard ratios (HR) for OS, DFS, and CSS were 1.09(95% confidence interval [CI]: 0.95–1.25; P = 0.215), 1.03(95% CI: 0.91–1.18; P = 0.636), and 1.07 (95% CI: 0.88–1.30; P = 0.484), respectively, compared LAP group with OP group. In conclusion, LAP is an acceptable alternative to OP in elderly patients with early gastric cancer.
format	article
author	Haiyan Pan Tao Li Zhigang Huang Haibing Yu Danli Kong Yuanlin Ding Congcong Pan Yugang Jiang
author_facet	Haiyan Pan Tao Li Zhigang Huang Haibing Yu Danli Kong Yuanlin Ding Congcong Pan Yugang Jiang
author_sort	Haiyan Pan
title	Laparoscopic versus opengastric surgery for the treatment of pathological T1N0M0 gastric cancer in elderly patients: a matched study
title_short	Laparoscopic versus opengastric surgery for the treatment of pathological T1N0M0 gastric cancer in elderly patients: a matched study
title_full	Laparoscopic versus opengastric surgery for the treatment of pathological T1N0M0 gastric cancer in elderly patients: a matched study
title_fullStr	Laparoscopic versus opengastric surgery for the treatment of pathological T1N0M0 gastric cancer in elderly patients: a matched study
title_full_unstemmed	Laparoscopic versus opengastric surgery for the treatment of pathological T1N0M0 gastric cancer in elderly patients: a matched study
title_sort	laparoscopic versus opengastric surgery for the treatment of pathological t1n0m0 gastric cancer in elderly patients: a matched study
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/ed3d5c0ba5b4496daebaf3a393674aa4
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Laparoscopic versus opengastric surgery for the treatment of pathological T1N0M0 gastric cancer in elderly patients: a matched study

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