A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech

Progressive apraxia of speech (PAOS) is a neurodegenerative syndrome of multiple etiologies which affects spoken communication. Here, the authors characterized the molecular pathology, biochemistry, genetics and longitudinal neuroimaging of 32 autopsy-confirmed patients with PAOS who were followed o...

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Autores principales: Keith A. Josephs, Joseph R. Duffy, Heather M. Clark, Rene L. Utianski, Edythe A. Strand, Mary M. Machulda, Hugo Botha, Peter R. Martin, Nha Trang Thu Pham, Julie Stierwalt, Farwa Ali, Marina Buciuc, Matthew Baker, Cristhoper H. Fernandez De Castro, Anthony J. Spychalla, Christopher G. Schwarz, Robert I. Reid, Matthew L. Senjem, Clifford R. Jack, Val J. Lowe, Eileen H. Bigio, Ross R. Reichard, Eric. J. Polley, Nilufer Ertekin-Taner, Rosa Rademakers, Michael A. DeTure, Owen A. Ross, Dennis W. Dickson, Jennifer L. Whitwell
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ed3e8ba520e446b7a84a4834659451e7
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spelling oai:doaj.org-article:ed3e8ba520e446b7a84a4834659451e72021-12-02T15:02:50ZA molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech10.1038/s41467-021-23687-82041-1723https://doaj.org/article/ed3e8ba520e446b7a84a4834659451e72021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23687-8https://doaj.org/toc/2041-1723Progressive apraxia of speech (PAOS) is a neurodegenerative syndrome of multiple etiologies which affects spoken communication. Here, the authors characterized the molecular pathology, biochemistry, genetics and longitudinal neuroimaging of 32 autopsy-confirmed patients with PAOS who were followed over 10 years.Keith A. JosephsJoseph R. DuffyHeather M. ClarkRene L. UtianskiEdythe A. StrandMary M. MachuldaHugo BothaPeter R. MartinNha Trang Thu PhamJulie StierwaltFarwa AliMarina BuciucMatthew BakerCristhoper H. Fernandez De CastroAnthony J. SpychallaChristopher G. SchwarzRobert I. ReidMatthew L. SenjemClifford R. JackVal J. LoweEileen H. BigioRoss R. ReichardEric. J. PolleyNilufer Ertekin-TanerRosa RademakersMichael A. DeTureOwen A. RossDennis W. DicksonJennifer L. WhitwellNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Keith A. Josephs
Joseph R. Duffy
Heather M. Clark
Rene L. Utianski
Edythe A. Strand
Mary M. Machulda
Hugo Botha
Peter R. Martin
Nha Trang Thu Pham
Julie Stierwalt
Farwa Ali
Marina Buciuc
Matthew Baker
Cristhoper H. Fernandez De Castro
Anthony J. Spychalla
Christopher G. Schwarz
Robert I. Reid
Matthew L. Senjem
Clifford R. Jack
Val J. Lowe
Eileen H. Bigio
Ross R. Reichard
Eric. J. Polley
Nilufer Ertekin-Taner
Rosa Rademakers
Michael A. DeTure
Owen A. Ross
Dennis W. Dickson
Jennifer L. Whitwell
A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech
description Progressive apraxia of speech (PAOS) is a neurodegenerative syndrome of multiple etiologies which affects spoken communication. Here, the authors characterized the molecular pathology, biochemistry, genetics and longitudinal neuroimaging of 32 autopsy-confirmed patients with PAOS who were followed over 10 years.
format article
author Keith A. Josephs
Joseph R. Duffy
Heather M. Clark
Rene L. Utianski
Edythe A. Strand
Mary M. Machulda
Hugo Botha
Peter R. Martin
Nha Trang Thu Pham
Julie Stierwalt
Farwa Ali
Marina Buciuc
Matthew Baker
Cristhoper H. Fernandez De Castro
Anthony J. Spychalla
Christopher G. Schwarz
Robert I. Reid
Matthew L. Senjem
Clifford R. Jack
Val J. Lowe
Eileen H. Bigio
Ross R. Reichard
Eric. J. Polley
Nilufer Ertekin-Taner
Rosa Rademakers
Michael A. DeTure
Owen A. Ross
Dennis W. Dickson
Jennifer L. Whitwell
author_facet Keith A. Josephs
Joseph R. Duffy
Heather M. Clark
Rene L. Utianski
Edythe A. Strand
Mary M. Machulda
Hugo Botha
Peter R. Martin
Nha Trang Thu Pham
Julie Stierwalt
Farwa Ali
Marina Buciuc
Matthew Baker
Cristhoper H. Fernandez De Castro
Anthony J. Spychalla
Christopher G. Schwarz
Robert I. Reid
Matthew L. Senjem
Clifford R. Jack
Val J. Lowe
Eileen H. Bigio
Ross R. Reichard
Eric. J. Polley
Nilufer Ertekin-Taner
Rosa Rademakers
Michael A. DeTure
Owen A. Ross
Dennis W. Dickson
Jennifer L. Whitwell
author_sort Keith A. Josephs
title A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech
title_short A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech
title_full A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech
title_fullStr A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech
title_full_unstemmed A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech
title_sort molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/ed3e8ba520e446b7a84a4834659451e7
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