Coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with Candida albicans

The outcomes of the interactions between individual host cells and pathogens are heterogeneous. Here, the authors assess transcriptional variability in both host and pathogen during infection of macrophages with the fungus Candida albicans, using sorted subpopulations and single macrophages.

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Autores principales:	José F. Muñoz, Toni Delorey, Christopher B. Ford, Bi Yu Li, Dawn A. Thompson, Reeta P. Rao, Christina A. Cuomo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ed4108988c524bcc93a97e3410c423b9
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spelling	oai:doaj.org-article:ed4108988c524bcc93a97e3410c423b92021-12-02T15:36:06ZCoordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with Candida albicans10.1038/s41467-019-09599-82041-1723https://doaj.org/article/ed4108988c524bcc93a97e3410c423b92019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09599-8https://doaj.org/toc/2041-1723The outcomes of the interactions between individual host cells and pathogens are heterogeneous. Here, the authors assess transcriptional variability in both host and pathogen during infection of macrophages with the fungus Candida albicans, using sorted subpopulations and single macrophages.José F. MuñozToni DeloreyChristopher B. FordBi Yu LiDawn A. ThompsonReeta P. RaoChristina A. CuomoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q José F. Muñoz Toni Delorey Christopher B. Ford Bi Yu Li Dawn A. Thompson Reeta P. Rao Christina A. Cuomo Coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with Candida albicans
description	The outcomes of the interactions between individual host cells and pathogens are heterogeneous. Here, the authors assess transcriptional variability in both host and pathogen during infection of macrophages with the fungus Candida albicans, using sorted subpopulations and single macrophages.
format	article
author	José F. Muñoz Toni Delorey Christopher B. Ford Bi Yu Li Dawn A. Thompson Reeta P. Rao Christina A. Cuomo
author_facet	José F. Muñoz Toni Delorey Christopher B. Ford Bi Yu Li Dawn A. Thompson Reeta P. Rao Christina A. Cuomo
author_sort	José F. Muñoz
title	Coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with Candida albicans
title_short	Coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with Candida albicans
title_full	Coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with Candida albicans
title_fullStr	Coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with Candida albicans
title_full_unstemmed	Coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with Candida albicans
title_sort	coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with candida albicans
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/ed4108988c524bcc93a97e3410c423b9
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Coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with Candida albicans

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