Cytotoxic aggregation and amyloid formation by the myostatin precursor protein.
Myostatin, a negative regulator of muscle growth, has been implicated in sporadic inclusion body myositis (sIBM). sIBM is the most common age-related muscle-wastage disease with a pathogenesis similar to that of amyloid disorders such as Alzheimer's and Parkinson's diseases. Myostatin prec...
Guardado en:
Autores principales: | Carlene S Starck, Andrew J Sutherland-Smith |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
|
Materias: | |
Acceso en línea: | https://doaj.org/article/ed445096ce704ad78357e39a095529c7 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Effects of Protein Corona on IAPP Amyloid Aggregation, Fibril Remodelling, and Cytotoxicity
por: Emily H. Pilkington, et al.
Publicado: (2017) -
A role for amyloid in cell aggregation and biofilm formation.
por: Melissa C Garcia, et al.
Publicado: (2011) -
Nanogels of dual inhibitor-modified hyaluronic acid function as a potent inhibitor of amyloid β-protein aggregation and cytotoxicity
por: Zhiqiang Jiang, et al.
Publicado: (2018) -
Generation of amyloid-β is reduced by the interaction of calreticulin with amyloid precursor protein, presenilin and nicastrin.
por: Nina Stemmer, et al.
Publicado: (2013) -
Amyloid precursor protein is trafficked and secreted via synaptic vesicles.
por: Teja W Groemer, et al.
Publicado: (2011)