High content analysis identifies unique morphological features of reprogrammed cardiomyocytes

Abstract Direct reprogramming of fibroblasts into cardiomyocytes is a promising approach for cardiac regeneration but still faces challenges in efficiently generating mature cardiomyocytes. Systematic optimization of reprogramming protocols requires scalable, objective methods to assess cellular phe...

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Bibliographic Details
Main Authors: Matthew D. Sutcliffe, Philip M. Tan, Antonio Fernandez-Perez, Young-Jae Nam, Nikhil V. Munshi, Jeffrey J. Saucerman
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
R
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Online Access:https://doaj.org/article/ed4cfada737b43d2ae2fd966138a9dc7
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