The <named-content content-type="genus-species">Aspergillus fumigatus</named-content> Damage Resistance Protein Family Coordinately Regulates Ergosterol Biosynthesis and Azole Susceptibility
ABSTRACT Ergosterol is a major and specific component of the fungal plasma membrane, and thus, the cytochrome P450 enzymes (Erg proteins) that catalyze ergosterol synthesis have been selected as valuable targets of azole antifungals. However, the opportunistic pathogen Aspergillus fumigatus has deve...
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Autores principales: | Jinxing Song, Pengfei Zhai, Yuanwei Zhang, Caiyun Zhang, Hong Sang, Guanzhu Han, Nancy P. Keller, Ling Lu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/ed51baa5307d48b4b1e2858ac2179a2e |
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