Agent Clustering Strategy Based on Metabolic Flux Distribution and Transcriptome Expression for Novel Drug Development
The network module-based method has been used for drug repositioning. The traditional drug repositioning method only uses the gene characteristics of the drug but ignores the drug-triggered metabolic changes. The metabolic network systematically characterizes the connection between genes, proteins,...
Guardado en:
Autores principales: | Yao Ruan, Xiao-Hui Chen, Feng Jiang, Yan-Guang Liu, Xiao-Long Liang, Bo-Min Lv, Hong-Yu Zhang, Qing-Ye Zhang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/ed57e0165d7141c3aeb66d734c476bdd |
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