Using nuclear receptor activity to stratify hepatocarcinogens.
<h4>Background</h4>Nuclear receptors (NR) are a superfamily of ligand-activated transcription factors that control a range of cellular processes. Persistent stimulation of some NR is a non-genotoxic mechanism of rodent liver cancer with unclear relevance to humans. Here we report on a sy...
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Autores principales: | Imran Shah, Keith Houck, Richard S Judson, Robert J Kavlock, Matthew T Martin, David M Reif, John Wambaugh, David J Dix |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/ed5c65908d7240b6ab1410db368238d9 |
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