Inhibition of Inflammasome-Dependent Interleukin 1β Production by Streptococcal NAD<sup>+</sup>-Glycohydrolase: Evidence for Extracellular Activity
ABSTRACT Group A Streptococcus (GAS) is a common human pathogen and the etiologic agent of a large number of diseases ranging from mild, self-limiting infections to invasive life-threatening conditions. Two prominent virulence factors of this bacterium are the genetically and functionally linked por...
Enregistré dans:
Auteurs principaux: | Dóra Hancz, Elsa Westerlund, Benedicte Bastiat-Sempe, Onkar Sharma, Christine Valfridsson, Lena Meyer, John F. Love, Maghnus O’Seaghdha, Michael R. Wessels, Jenny J. Persson |
---|---|
Format: | article |
Langue: | EN |
Publié: |
American Society for Microbiology
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/ed60a73db88044dd80ac2bc414eea6eb |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Binding of NAD<sup>+</sup>-Glycohydrolase to Streptolysin O Stabilizes Both Toxins and Promotes Virulence of Group A <italic toggle="yes">Streptococcus</italic>
par: Jorge J. Velarde, et autres
Publié: (2017) -
Streptolysin O and NAD-Glycohydrolase Prevent Phagolysosome Acidification and Promote Group A <italic toggle="yes">Streptococcus</italic> Survival in Macrophages
par: Benedicte Bastiat-Sempe, et autres
Publié: (2014) -
NAD<sup>+</sup> Metabolism and Diseases with Motor Dysfunction
par: Samuel Lundt, et autres
Publié: (2021) -
LOCAL IMMUNITY PATTERNS IN PURULENT WOUNDS
par: K. V. Shmagel, et autres
Publié: (2014) -
An Experimental Group A <italic toggle="yes">Streptococcus</italic> Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model
par: Tania Rivera-Hernandez, et autres
Publié: (2019)