Chromatin remodelling and antisense-mediated up-regulation of the developmental switch gene eud-1 control predatory feeding plasticity

In the nematode Pristionchus pacificus, a developmental switch, the sulfatase eud-1, controls mouth-form plasticity. Here, the authors show that mutations in two conserved histone modifying enzymes mimic the eud-1 phenotype, in part mediated by an antisense eud-1RNA, resulting in the absence of one...

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Autores principales: Vahan Serobyan, Hua Xiao, Suryesh Namdeo, Christian Rödelsperger, Bogdan Sieriebriennikov, Hanh Witte, Waltraud Röseler, Ralf J. Sommer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/ed65dc4eeab7458dad3ada9599b1f9b9
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Sumario:In the nematode Pristionchus pacificus, a developmental switch, the sulfatase eud-1, controls mouth-form plasticity. Here, the authors show that mutations in two conserved histone modifying enzymes mimic the eud-1 phenotype, in part mediated by an antisense eud-1RNA, resulting in the absence of one mouth-form