Cell entry of a host-targeting protein of oomycetes requires gp96

The pathogenic oomycete Saprolegnia parasitica secretes effector proteins that translocate into host cells through unclear mechanisms. Here, Trusch et al. show that the uptake of effector protein SpHtp3, resulting in RNA degradation, depends on a gp96-like host receptor and a second effector protein...

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Autores principales:	Franziska Trusch, Lars Loebach, Stephan Wawra, Elaine Durward, Andreas Wuensch, Nurul Aqilah Iberahim, Irene de Bruijn, Kevin MacKenzie, Ariane Willems, Aleksandra Toloczko, Javier Diéguez-Uribeondo, Tim Rasmussen, Thomas Schrader, Peter Bayer, Chris J. Secombes, Pieter van West
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ed66e4d7e30d4723b810b283c5eb1678
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spelling	oai:doaj.org-article:ed66e4d7e30d4723b810b283c5eb16782021-12-02T17:32:29ZCell entry of a host-targeting protein of oomycetes requires gp9610.1038/s41467-018-04796-32041-1723https://doaj.org/article/ed66e4d7e30d4723b810b283c5eb16782018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04796-3https://doaj.org/toc/2041-1723The pathogenic oomycete Saprolegnia parasitica secretes effector proteins that translocate into host cells through unclear mechanisms. Here, Trusch et al. show that the uptake of effector protein SpHtp3, resulting in RNA degradation, depends on a gp96-like host receptor and a second effector protein.Franziska TruschLars LoebachStephan WawraElaine DurwardAndreas WuenschNurul Aqilah IberahimIrene de BruijnKevin MacKenzieAriane WillemsAleksandra ToloczkoJavier Diéguez-UribeondoTim RasmussenThomas SchraderPeter BayerChris J. SecombesPieter van WestNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Franziska Trusch Lars Loebach Stephan Wawra Elaine Durward Andreas Wuensch Nurul Aqilah Iberahim Irene de Bruijn Kevin MacKenzie Ariane Willems Aleksandra Toloczko Javier Diéguez-Uribeondo Tim Rasmussen Thomas Schrader Peter Bayer Chris J. Secombes Pieter van West Cell entry of a host-targeting protein of oomycetes requires gp96
description	The pathogenic oomycete Saprolegnia parasitica secretes effector proteins that translocate into host cells through unclear mechanisms. Here, Trusch et al. show that the uptake of effector protein SpHtp3, resulting in RNA degradation, depends on a gp96-like host receptor and a second effector protein.
format	article
author	Franziska Trusch Lars Loebach Stephan Wawra Elaine Durward Andreas Wuensch Nurul Aqilah Iberahim Irene de Bruijn Kevin MacKenzie Ariane Willems Aleksandra Toloczko Javier Diéguez-Uribeondo Tim Rasmussen Thomas Schrader Peter Bayer Chris J. Secombes Pieter van West
author_facet	Franziska Trusch Lars Loebach Stephan Wawra Elaine Durward Andreas Wuensch Nurul Aqilah Iberahim Irene de Bruijn Kevin MacKenzie Ariane Willems Aleksandra Toloczko Javier Diéguez-Uribeondo Tim Rasmussen Thomas Schrader Peter Bayer Chris J. Secombes Pieter van West
author_sort	Franziska Trusch
title	Cell entry of a host-targeting protein of oomycetes requires gp96
title_short	Cell entry of a host-targeting protein of oomycetes requires gp96
title_full	Cell entry of a host-targeting protein of oomycetes requires gp96
title_fullStr	Cell entry of a host-targeting protein of oomycetes requires gp96
title_full_unstemmed	Cell entry of a host-targeting protein of oomycetes requires gp96
title_sort	cell entry of a host-targeting protein of oomycetes requires gp96
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/ed66e4d7e30d4723b810b283c5eb1678
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Cell entry of a host-targeting protein of oomycetes requires gp96

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