Calcium-Phosphate Metabolism Disorders in Patients with Renal Failure Clinical Significance, Diagnosis and Treatment

Chronic kidney diseases (CKD) are commonly associated with calcium and phosphorus metabolism disorders. The general term of “renal osteodystrophy” (ROD) encompasses a complex spectrum of abnormalities in bone and mineral metabolism in CKD. This is one of the most serious and debilitating complicatio...

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Autores principales:	Grozeva V., Kundurzhiev A.
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2019
Materias:	calcium-phosphate metabolism chronic kidney diseases hyperparathyroidism Medicine R
Acceso en línea:	https://doaj.org/article/ed705412c89b47c895960e664d3bbcf2
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spelling	oai:doaj.org-article:ed705412c89b47c895960e664d3bbcf22021-12-02T19:11:32ZCalcium-Phosphate Metabolism Disorders in Patients with Renal Failure Clinical Significance, Diagnosis and Treatment0324-175010.2478/amb-2019-0009https://doaj.org/article/ed705412c89b47c895960e664d3bbcf22019-02-01T00:00:00Zhttps://doi.org/10.2478/amb-2019-0009https://doaj.org/toc/0324-1750Chronic kidney diseases (CKD) are commonly associated with calcium and phosphorus metabolism disorders. The general term of “renal osteodystrophy” (ROD) encompasses a complex spectrum of abnormalities in bone and mineral metabolism in CKD. This is one of the most serious and debilitating complications of CKD. It is related to disproportionately high direct and indirect costs of healthcare, thus posing a major burden on society. The development of ROD begins too early in the course of CKD. Some mechanisms involved in the pathogenesis of ROD are reduced calciferol production, calcium deficiency and hyperphosphatemia. Clinically, ROD occurs with varied manifestations – osteomalacia, osteoporosis, adynamic bone disease. The diagnosis and the treatment are a challenge for the physician and effort should be made to prolong the duration and quality of life of the affected patients.Grozeva V.Kundurzhiev A.Sciendoarticlecalcium-phosphate metabolismchronic kidney diseaseshyperparathyroidismMedicineRENActa Medica Bulgarica, Vol 46, Iss 1, Pp 50-56 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	calcium-phosphate metabolism chronic kidney diseases hyperparathyroidism Medicine R
spellingShingle	calcium-phosphate metabolism chronic kidney diseases hyperparathyroidism Medicine R Grozeva V. Kundurzhiev A. Calcium-Phosphate Metabolism Disorders in Patients with Renal Failure Clinical Significance, Diagnosis and Treatment
description	Chronic kidney diseases (CKD) are commonly associated with calcium and phosphorus metabolism disorders. The general term of “renal osteodystrophy” (ROD) encompasses a complex spectrum of abnormalities in bone and mineral metabolism in CKD. This is one of the most serious and debilitating complications of CKD. It is related to disproportionately high direct and indirect costs of healthcare, thus posing a major burden on society. The development of ROD begins too early in the course of CKD. Some mechanisms involved in the pathogenesis of ROD are reduced calciferol production, calcium deficiency and hyperphosphatemia. Clinically, ROD occurs with varied manifestations – osteomalacia, osteoporosis, adynamic bone disease. The diagnosis and the treatment are a challenge for the physician and effort should be made to prolong the duration and quality of life of the affected patients.
format	article
author	Grozeva V. Kundurzhiev A.
author_facet	Grozeva V. Kundurzhiev A.
author_sort	Grozeva V.
title	Calcium-Phosphate Metabolism Disorders in Patients with Renal Failure Clinical Significance, Diagnosis and Treatment
title_short	Calcium-Phosphate Metabolism Disorders in Patients with Renal Failure Clinical Significance, Diagnosis and Treatment
title_full	Calcium-Phosphate Metabolism Disorders in Patients with Renal Failure Clinical Significance, Diagnosis and Treatment
title_fullStr	Calcium-Phosphate Metabolism Disorders in Patients with Renal Failure Clinical Significance, Diagnosis and Treatment
title_full_unstemmed	Calcium-Phosphate Metabolism Disorders in Patients with Renal Failure Clinical Significance, Diagnosis and Treatment
title_sort	calcium-phosphate metabolism disorders in patients with renal failure clinical significance, diagnosis and treatment
publisher	Sciendo
publishDate	2019
url	https://doaj.org/article/ed705412c89b47c895960e664d3bbcf2
work_keys_str_mv	AT grozevav calciumphosphatemetabolismdisordersinpatientswithrenalfailureclinicalsignificancediagnosisandtreatment AT kundurzhieva calciumphosphatemetabolismdisordersinpatientswithrenalfailureclinicalsignificancediagnosisandtreatment
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Calcium-Phosphate Metabolism Disorders in Patients with Renal Failure Clinical Significance, Diagnosis and Treatment

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