EcR recruits dMi-2 and increases efficiency of dMi-2-mediated remodelling to constrain transcription of hormone-regulated genes

InDrosophila, ecdysone-regulated genes are bound by a heterodimer of ecdysone receptor (EcR) and Ultraspiracle. Here, the authors provide evidence of a non-canonical complex containing EcR and the nucleosome remodeller dMi-2 that limits transcription of ecdysone-regulated genes.

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Autores principales:	Judith Kreher, Kristina Kovač, Karim Bouazoune, Igor Mačinković, Anna Luise Ernst, Erik Engelen, Roman Pahl, Florian Finkernagel, Magdalena Murawska, Ikram Ullah, Alexander Brehm
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ed8c40e137794af48d7a705dffd88ec5
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spelling	oai:doaj.org-article:ed8c40e137794af48d7a705dffd88ec52021-12-02T17:06:11ZEcR recruits dMi-2 and increases efficiency of dMi-2-mediated remodelling to constrain transcription of hormone-regulated genes10.1038/ncomms148062041-1723https://doaj.org/article/ed8c40e137794af48d7a705dffd88ec52017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms14806https://doaj.org/toc/2041-1723InDrosophila, ecdysone-regulated genes are bound by a heterodimer of ecdysone receptor (EcR) and Ultraspiracle. Here, the authors provide evidence of a non-canonical complex containing EcR and the nucleosome remodeller dMi-2 that limits transcription of ecdysone-regulated genes.Judith KreherKristina KovačKarim BouazouneIgor MačinkovićAnna Luise ErnstErik EngelenRoman PahlFlorian FinkernagelMagdalena MurawskaIkram UllahAlexander BrehmNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Judith Kreher Kristina Kovač Karim Bouazoune Igor Mačinković Anna Luise Ernst Erik Engelen Roman Pahl Florian Finkernagel Magdalena Murawska Ikram Ullah Alexander Brehm EcR recruits dMi-2 and increases efficiency of dMi-2-mediated remodelling to constrain transcription of hormone-regulated genes
description	InDrosophila, ecdysone-regulated genes are bound by a heterodimer of ecdysone receptor (EcR) and Ultraspiracle. Here, the authors provide evidence of a non-canonical complex containing EcR and the nucleosome remodeller dMi-2 that limits transcription of ecdysone-regulated genes.
format	article
author	Judith Kreher Kristina Kovač Karim Bouazoune Igor Mačinković Anna Luise Ernst Erik Engelen Roman Pahl Florian Finkernagel Magdalena Murawska Ikram Ullah Alexander Brehm
author_facet	Judith Kreher Kristina Kovač Karim Bouazoune Igor Mačinković Anna Luise Ernst Erik Engelen Roman Pahl Florian Finkernagel Magdalena Murawska Ikram Ullah Alexander Brehm
author_sort	Judith Kreher
title	EcR recruits dMi-2 and increases efficiency of dMi-2-mediated remodelling to constrain transcription of hormone-regulated genes
title_short	EcR recruits dMi-2 and increases efficiency of dMi-2-mediated remodelling to constrain transcription of hormone-regulated genes
title_full	EcR recruits dMi-2 and increases efficiency of dMi-2-mediated remodelling to constrain transcription of hormone-regulated genes
title_fullStr	EcR recruits dMi-2 and increases efficiency of dMi-2-mediated remodelling to constrain transcription of hormone-regulated genes
title_full_unstemmed	EcR recruits dMi-2 and increases efficiency of dMi-2-mediated remodelling to constrain transcription of hormone-regulated genes
title_sort	ecr recruits dmi-2 and increases efficiency of dmi-2-mediated remodelling to constrain transcription of hormone-regulated genes
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/ed8c40e137794af48d7a705dffd88ec5
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EcR recruits dMi-2 and increases efficiency of dMi-2-mediated remodelling to constrain transcription of hormone-regulated genes

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