Neutrophil polarization by IL-27 as a therapeutic target for intracerebral hemorrhage

Neutrophils are important modulators of tissue damage after intracerebral hemorrhage (ICH), but how this function is regulated is not clear. Here, the authors show interleukin-27 promotes the tissue-protecting functions of neutrophils via, at least partly, the induction of lactoferrin to present a p...

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Autores principales:	Xiurong Zhao, Shun-Ming Ting, Chin-Hsuan Liu, Guanghua Sun, Marian Kruzel, Meaghan Roy-O’Reilly, Jaroslaw Aronowski
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ed8ca05aea3a4250bce07510d1521b54
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spelling	oai:doaj.org-article:ed8ca05aea3a4250bce07510d1521b542021-12-02T14:42:42ZNeutrophil polarization by IL-27 as a therapeutic target for intracerebral hemorrhage10.1038/s41467-017-00770-72041-1723https://doaj.org/article/ed8ca05aea3a4250bce07510d1521b542017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00770-7https://doaj.org/toc/2041-1723Neutrophils are important modulators of tissue damage after intracerebral hemorrhage (ICH), but how this function is regulated is not clear. Here, the authors show interleukin-27 promotes the tissue-protecting functions of neutrophils via, at least partly, the induction of lactoferrin to present a potential therapy for ICH.Xiurong ZhaoShun-Ming TingChin-Hsuan LiuGuanghua SunMarian KruzelMeaghan Roy-O’ReillyJaroslaw AronowskiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiurong Zhao Shun-Ming Ting Chin-Hsuan Liu Guanghua Sun Marian Kruzel Meaghan Roy-O’Reilly Jaroslaw Aronowski Neutrophil polarization by IL-27 as a therapeutic target for intracerebral hemorrhage
description	Neutrophils are important modulators of tissue damage after intracerebral hemorrhage (ICH), but how this function is regulated is not clear. Here, the authors show interleukin-27 promotes the tissue-protecting functions of neutrophils via, at least partly, the induction of lactoferrin to present a potential therapy for ICH.
format	article
author	Xiurong Zhao Shun-Ming Ting Chin-Hsuan Liu Guanghua Sun Marian Kruzel Meaghan Roy-O’Reilly Jaroslaw Aronowski
author_facet	Xiurong Zhao Shun-Ming Ting Chin-Hsuan Liu Guanghua Sun Marian Kruzel Meaghan Roy-O’Reilly Jaroslaw Aronowski
author_sort	Xiurong Zhao
title	Neutrophil polarization by IL-27 as a therapeutic target for intracerebral hemorrhage
title_short	Neutrophil polarization by IL-27 as a therapeutic target for intracerebral hemorrhage
title_full	Neutrophil polarization by IL-27 as a therapeutic target for intracerebral hemorrhage
title_fullStr	Neutrophil polarization by IL-27 as a therapeutic target for intracerebral hemorrhage
title_full_unstemmed	Neutrophil polarization by IL-27 as a therapeutic target for intracerebral hemorrhage
title_sort	neutrophil polarization by il-27 as a therapeutic target for intracerebral hemorrhage
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/ed8ca05aea3a4250bce07510d1521b54
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Neutrophil polarization by IL-27 as a therapeutic target for intracerebral hemorrhage

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