The Influence of Plants from the <i>Alliaceae</i> Family on Morphological Parameters of the Intestine in Atherogenic Rats

Bulbs from the <i>Alliaceae</i> family have been well-known and valued spices for thousands of years, not only for their unique flavor and aroma features, but also for their high nutritional and health-promoting values. Long-term or excessive consumption of these vegetables, especially r...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Katarzyna Najman, Hanna Leontowicz, Maria Leontowicz
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	garlic (<i>Allium sativum</i> L.) onion (<i>Allium cepa</i> L.) Wistar rat cholesterol atherosclerosis ileum Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/ed8dab9e0dcc48079bf22037feb9ffed
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ed8dab9e0dcc48079bf22037feb9ffed
record_format	dspace
spelling	oai:doaj.org-article:ed8dab9e0dcc48079bf22037feb9ffed2021-11-25T18:34:53ZThe Influence of Plants from the <i>Alliaceae</i> Family on Morphological Parameters of the Intestine in Atherogenic Rats10.3390/nu131138762072-6643https://doaj.org/article/ed8dab9e0dcc48079bf22037feb9ffed2021-10-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/3876https://doaj.org/toc/2072-6643Bulbs from the <i>Alliaceae</i> family have been well-known and valued spices for thousands of years, not only for their unique flavor and aroma features, but also for their high nutritional and health-promoting values. Long-term or excessive consumption of these vegetables, especially raw garlic, can have side effects in the body (including in the digestive tract), causing a number of pathological changes in the intestinal wall; these changes lead, in turn, to its damage, dysfunction, and disorder development. Therefore, the aim of this study was to investigate the effect of the addition of freeze-dried vegetables from the <i>Alliaceae</i> family, i.e., garlic (<i>Allium sativum</i> L.), white onion, and red onion (<i>Allium cepa</i> L.) on the morphometric parameters (intestinal villi length, crypt depth, thickness of tunica mucosa, and the thickness of tunica muscle) of the jejunum of rats fed a semi-synthetic atherogenic diet (1% dietary cholesterol). In freeze-dried vegetables administered to rats, the contents of selected bioactive ingredients and their antioxidant potentials were determined. The effect of the onion vegetable supplements on growth parameters, serum lipid profile, plasma antioxidant potential, and the intestinal morphological parameters of rats loaded with cholesterol was determined. In an animal experiment, 30 male Wistar rats were divided into 5 diet groups, diet consumption and FER were studied. Supplementation of the atherogenic diet with vegetables improved the blood plasma lipid profiles and atherogenic indices, in a manner that was dependent on the type of supplementation used, with the best hypolipidemic and anti-atherosclerotic effects found in garlic use. The atherogenic diet, as well as the supplementation of this diet with the tested vegetables from the <i>Alliaceae</i> family, influenced the histological changes in the epithelium of the jejunum of rats. The damage to the intestinal mucosa was the greatest in animals fed an atherogenic diet supplemented with garlic. Bearing in mind that the desired beneficial therapeutic or prophylactic effects of onion vegetables (in particular garlic) in the course of various metabolic ailments (including atherosclerosis) are achieved during long-term supplementation, it is important to remember their possible cytotoxic effects (e.g., on the digestive tract) in order to achieve real benefits related to the supplementation with vegetables from the <i>Alliaceae</i> family.Katarzyna NajmanHanna LeontowiczMaria LeontowiczMDPI AGarticlegarlic (<i>Allium sativum</i> L.)onion (<i>Allium cepa</i> L.)Wistar ratcholesterolatherosclerosisileumNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 3876, p 3876 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	garlic (<i>Allium sativum</i> L.) onion (<i>Allium cepa</i> L.) Wistar rat cholesterol atherosclerosis ileum Nutrition. Foods and food supply TX341-641
spellingShingle	garlic (<i>Allium sativum</i> L.) onion (<i>Allium cepa</i> L.) Wistar rat cholesterol atherosclerosis ileum Nutrition. Foods and food supply TX341-641 Katarzyna Najman Hanna Leontowicz Maria Leontowicz The Influence of Plants from the <i>Alliaceae</i> Family on Morphological Parameters of the Intestine in Atherogenic Rats
description	Bulbs from the <i>Alliaceae</i> family have been well-known and valued spices for thousands of years, not only for their unique flavor and aroma features, but also for their high nutritional and health-promoting values. Long-term or excessive consumption of these vegetables, especially raw garlic, can have side effects in the body (including in the digestive tract), causing a number of pathological changes in the intestinal wall; these changes lead, in turn, to its damage, dysfunction, and disorder development. Therefore, the aim of this study was to investigate the effect of the addition of freeze-dried vegetables from the <i>Alliaceae</i> family, i.e., garlic (<i>Allium sativum</i> L.), white onion, and red onion (<i>Allium cepa</i> L.) on the morphometric parameters (intestinal villi length, crypt depth, thickness of tunica mucosa, and the thickness of tunica muscle) of the jejunum of rats fed a semi-synthetic atherogenic diet (1% dietary cholesterol). In freeze-dried vegetables administered to rats, the contents of selected bioactive ingredients and their antioxidant potentials were determined. The effect of the onion vegetable supplements on growth parameters, serum lipid profile, plasma antioxidant potential, and the intestinal morphological parameters of rats loaded with cholesterol was determined. In an animal experiment, 30 male Wistar rats were divided into 5 diet groups, diet consumption and FER were studied. Supplementation of the atherogenic diet with vegetables improved the blood plasma lipid profiles and atherogenic indices, in a manner that was dependent on the type of supplementation used, with the best hypolipidemic and anti-atherosclerotic effects found in garlic use. The atherogenic diet, as well as the supplementation of this diet with the tested vegetables from the <i>Alliaceae</i> family, influenced the histological changes in the epithelium of the jejunum of rats. The damage to the intestinal mucosa was the greatest in animals fed an atherogenic diet supplemented with garlic. Bearing in mind that the desired beneficial therapeutic or prophylactic effects of onion vegetables (in particular garlic) in the course of various metabolic ailments (including atherosclerosis) are achieved during long-term supplementation, it is important to remember their possible cytotoxic effects (e.g., on the digestive tract) in order to achieve real benefits related to the supplementation with vegetables from the <i>Alliaceae</i> family.
format	article
author	Katarzyna Najman Hanna Leontowicz Maria Leontowicz
author_facet	Katarzyna Najman Hanna Leontowicz Maria Leontowicz
author_sort	Katarzyna Najman
title	The Influence of Plants from the <i>Alliaceae</i> Family on Morphological Parameters of the Intestine in Atherogenic Rats
title_short	The Influence of Plants from the <i>Alliaceae</i> Family on Morphological Parameters of the Intestine in Atherogenic Rats
title_full	The Influence of Plants from the <i>Alliaceae</i> Family on Morphological Parameters of the Intestine in Atherogenic Rats
title_fullStr	The Influence of Plants from the <i>Alliaceae</i> Family on Morphological Parameters of the Intestine in Atherogenic Rats
title_full_unstemmed	The Influence of Plants from the <i>Alliaceae</i> Family on Morphological Parameters of the Intestine in Atherogenic Rats
title_sort	influence of plants from the <i>alliaceae</i> family on morphological parameters of the intestine in atherogenic rats
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/ed8dab9e0dcc48079bf22037feb9ffed
work_keys_str_mv	AT katarzynanajman theinfluenceofplantsfromtheialliaceaeifamilyonmorphologicalparametersoftheintestineinatherogenicrats AT hannaleontowicz theinfluenceofplantsfromtheialliaceaeifamilyonmorphologicalparametersoftheintestineinatherogenicrats AT marialeontowicz theinfluenceofplantsfromtheialliaceaeifamilyonmorphologicalparametersoftheintestineinatherogenicrats AT katarzynanajman influenceofplantsfromtheialliaceaeifamilyonmorphologicalparametersoftheintestineinatherogenicrats AT hannaleontowicz influenceofplantsfromtheialliaceaeifamilyonmorphologicalparametersoftheintestineinatherogenicrats AT marialeontowicz influenceofplantsfromtheialliaceaeifamilyonmorphologicalparametersoftheintestineinatherogenicrats
_version_	1718410987235704832

The Influence of Plants from the <i>Alliaceae</i> Family on Morphological Parameters of the Intestine in Atherogenic Rats

Ejemplares similares