Proposal of a novel classification of leukocorias

Marcia Beatriz Tartarella,1 Gl&oacute;ria F&aacute;tima Britez-Colombi,1 Jo&atilde;o Borges Fortes Filho21Department of Ophthalmology, Congenital Cataract Section, Federal University of S&atilde;o Paulo, S&atilde;o Paulo SP, Brazil; 2Department of Ophthalmolog...

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Autores principales:	Tartarella MB, Britez-Colombi GF, Fortes Filho JB
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/ed8fc75bc5b746cfb912897df0775029
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spelling	oai:doaj.org-article:ed8fc75bc5b746cfb912897df07750292021-12-02T04:35:02ZProposal of a novel classification of leukocorias1177-54671177-5483https://doaj.org/article/ed8fc75bc5b746cfb912897df07750292012-06-01T00:00:00Zhttp://www.dovepress.com/proposal-of-a-novel-classification-of-leukocorias-a10258https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Marcia Beatriz Tartarella,1 Gl&oacute;ria F&aacute;tima Britez-Colombi,1 Jo&atilde;o Borges Fortes Filho21Department of Ophthalmology, Congenital Cataract Section, Federal University of S&atilde;o Paulo, S&atilde;o Paulo SP, Brazil; 2Department of Ophthalmology, Hospital de Cl&iacute;nicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre RS, BrazilBackground: To report a case series of nine patients presenting with leukocoria without lens opacification or retrolental abnormalities and to propose a novel classification for leukocoria.Methods: An institutional and retrospective study including a case series of patients assisted in the Congenital Cataract Section of Federal University of S&atilde;o Paulo, Brazil, during the period between 2005 and 2010 with prelenticular leukocoria and clear lens.Results: Nine patients younger than 4 years old presented with the diagnosis of unilateral prelenticular opacities without cataract formation. Echography in all patients revealed no posterior segment or lens abnormalities in the affected eye. Among the patients, three had idiopathic prelenticular membrane, two presented with juvenile xanthogranuloma with secondary pupillary membrane, one had persistent fetal pupillary membrane, one had prelenticular membrane due to congenital toxoplasmosis, one presented with pupillary membrane due to hyphema caused by iris hemangioma, and one had anterior segment persistent fetal vasculature.Conclusions: This case series of patients presented unilateral prelenticular leukocoria without lens opacification or posterior segment abnormalities. Several etiologies were associated with this condition. The correct diagnosis is important in order to avoid clear lens extraction. A new classification of leukocoria is proposed herein including: prelenticular leukocoria, lenticular leukocoria, retrolenticular leukocoria, and mixed presentation leukocoria.Keywords: leukocoria, prelenticular, pupillary membrane, children, retinoblastoma, congenital cataractTartarella MBBritez-Colombi GFFortes Filho JBDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 991-995 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Tartarella MB Britez-Colombi GF Fortes Filho JB Proposal of a novel classification of leukocorias
description	Marcia Beatriz Tartarella,1 Gl&oacute;ria F&aacute;tima Britez-Colombi,1 Jo&atilde;o Borges Fortes Filho21Department of Ophthalmology, Congenital Cataract Section, Federal University of S&atilde;o Paulo, S&atilde;o Paulo SP, Brazil; 2Department of Ophthalmology, Hospital de Cl&iacute;nicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre RS, BrazilBackground: To report a case series of nine patients presenting with leukocoria without lens opacification or retrolental abnormalities and to propose a novel classification for leukocoria.Methods: An institutional and retrospective study including a case series of patients assisted in the Congenital Cataract Section of Federal University of S&atilde;o Paulo, Brazil, during the period between 2005 and 2010 with prelenticular leukocoria and clear lens.Results: Nine patients younger than 4 years old presented with the diagnosis of unilateral prelenticular opacities without cataract formation. Echography in all patients revealed no posterior segment or lens abnormalities in the affected eye. Among the patients, three had idiopathic prelenticular membrane, two presented with juvenile xanthogranuloma with secondary pupillary membrane, one had persistent fetal pupillary membrane, one had prelenticular membrane due to congenital toxoplasmosis, one presented with pupillary membrane due to hyphema caused by iris hemangioma, and one had anterior segment persistent fetal vasculature.Conclusions: This case series of patients presented unilateral prelenticular leukocoria without lens opacification or posterior segment abnormalities. Several etiologies were associated with this condition. The correct diagnosis is important in order to avoid clear lens extraction. A new classification of leukocoria is proposed herein including: prelenticular leukocoria, lenticular leukocoria, retrolenticular leukocoria, and mixed presentation leukocoria.Keywords: leukocoria, prelenticular, pupillary membrane, children, retinoblastoma, congenital cataract
format	article
author	Tartarella MB Britez-Colombi GF Fortes Filho JB
author_facet	Tartarella MB Britez-Colombi GF Fortes Filho JB
author_sort	Tartarella MB
title	Proposal of a novel classification of leukocorias
title_short	Proposal of a novel classification of leukocorias
title_full	Proposal of a novel classification of leukocorias
title_fullStr	Proposal of a novel classification of leukocorias
title_full_unstemmed	Proposal of a novel classification of leukocorias
title_sort	proposal of a novel classification of leukocorias
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/ed8fc75bc5b746cfb912897df0775029
work_keys_str_mv	AT tartarellamb proposalofanovelclassificationofleukocorias AT britezcolombigf proposalofanovelclassificationofleukocorias AT fortesfilhojb proposalofanovelclassificationofleukocorias
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Proposal of a novel classification of leukocorias

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