Overexpression and small molecule-triggered downregulation of CIP2A in lung cancer.

Overexpression and small molecule-triggered downregulation of CIP2A in lung cancer.

<h4>Background</h4>Lung cancer is the leading cause of cancer deaths worldwide, with a five-year overall survival rate of only 15%. Cancerous inhibitor of PP2A (CIP2A) is a human oncoprotein inhibiting PP2A in many human malignancies. However, whether CIP2A can be a new drug target for l...

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Autores principales: Liang Ma, Zhe-Sheng Wen, Zi Liu, Zheng Hu, Jun Ma, Xiao-Qin Chen, Yong-Qiang Liu, Jian-Xin Pu, Wei-Lie Xiao, Han-Dong Sun, Guang-Biao Zhou
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/ed9f011dd4fd4b52af44468804763a4e
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