Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function

Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function

N-docosahexaenoylethanolamine (synaptamide) promotes neurogenesis but the molecular mechanism involved is unknown. Here, the authors show that orphan G-protein coupled receptor 110 is the synaptamide receptor, with deletion in mice affecting development of neurons, object recognition and spatial mem...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Ji-Won Lee, Bill X. Huang, HeungSun Kwon, Md Abdur Rashid, Giorgi Kharebava, Abhishek Desai, Samarjit Patnaik, Juan Marugan, Hee-Yong Kim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/eda1618c0c6741bbac8ea7b6da510a61
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:eda1618c0c6741bbac8ea7b6da510a61
record_format dspace
spelling oai:doaj.org-article:eda1618c0c6741bbac8ea7b6da510a612021-12-02T17:33:20ZOrphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function10.1038/ncomms131232041-1723https://doaj.org/article/eda1618c0c6741bbac8ea7b6da510a612016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13123https://doaj.org/toc/2041-1723N-docosahexaenoylethanolamine (synaptamide) promotes neurogenesis but the molecular mechanism involved is unknown. Here, the authors show that orphan G-protein coupled receptor 110 is the synaptamide receptor, with deletion in mice affecting development of neurons, object recognition and spatial memory.Ji-Won LeeBill X. HuangHeungSun KwonMd Abdur RashidGiorgi KharebavaAbhishek DesaiSamarjit PatnaikJuan MaruganHee-Yong KimNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ji-Won Lee
Bill X. Huang
HeungSun Kwon
Md Abdur Rashid
Giorgi Kharebava
Abhishek Desai
Samarjit Patnaik
Juan Marugan
Hee-Yong Kim
Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function
description N-docosahexaenoylethanolamine (synaptamide) promotes neurogenesis but the molecular mechanism involved is unknown. Here, the authors show that orphan G-protein coupled receptor 110 is the synaptamide receptor, with deletion in mice affecting development of neurons, object recognition and spatial memory.
format article
author Ji-Won Lee
Bill X. Huang
HeungSun Kwon
Md Abdur Rashid
Giorgi Kharebava
Abhishek Desai
Samarjit Patnaik
Juan Marugan
Hee-Yong Kim
author_facet Ji-Won Lee
Bill X. Huang
HeungSun Kwon
Md Abdur Rashid
Giorgi Kharebava
Abhishek Desai
Samarjit Patnaik
Juan Marugan
Hee-Yong Kim
author_sort Ji-Won Lee
title Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function
title_short Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function
title_full Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function
title_fullStr Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function
title_full_unstemmed Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function
title_sort orphan gpr110 (adgrf1) targeted by n-docosahexaenoylethanolamine in development of neurons and cognitive function
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/eda1618c0c6741bbac8ea7b6da510a61
work_keys_str_mv AT jiwonlee orphangpr110adgrf1targetedbyndocosahexaenoylethanolamineindevelopmentofneuronsandcognitivefunction
AT billxhuang orphangpr110adgrf1targetedbyndocosahexaenoylethanolamineindevelopmentofneuronsandcognitivefunction
AT heungsunkwon orphangpr110adgrf1targetedbyndocosahexaenoylethanolamineindevelopmentofneuronsandcognitivefunction
AT mdabdurrashid orphangpr110adgrf1targetedbyndocosahexaenoylethanolamineindevelopmentofneuronsandcognitivefunction
AT giorgikharebava orphangpr110adgrf1targetedbyndocosahexaenoylethanolamineindevelopmentofneuronsandcognitivefunction
AT abhishekdesai orphangpr110adgrf1targetedbyndocosahexaenoylethanolamineindevelopmentofneuronsandcognitivefunction
AT samarjitpatnaik orphangpr110adgrf1targetedbyndocosahexaenoylethanolamineindevelopmentofneuronsandcognitivefunction
AT juanmarugan orphangpr110adgrf1targetedbyndocosahexaenoylethanolamineindevelopmentofneuronsandcognitivefunction
AT heeyongkim orphangpr110adgrf1targetedbyndocosahexaenoylethanolamineindevelopmentofneuronsandcognitivefunction
_version_ 1718379974125158400

Ejemplares similares