Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function

Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function

N-docosahexaenoylethanolamine (synaptamide) promotes neurogenesis but the molecular mechanism involved is unknown. Here, the authors show that orphan G-protein coupled receptor 110 is the synaptamide receptor, with deletion in mice affecting development of neurons, object recognition and spatial mem...

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Autores principales: Ji-Won Lee, Bill X. Huang, HeungSun Kwon, Md Abdur Rashid, Giorgi Kharebava, Abhishek Desai, Samarjit Patnaik, Juan Marugan, Hee-Yong Kim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/eda1618c0c6741bbac8ea7b6da510a61
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