FOXP3+ T cells in uterine sarcomas are associated with favorable prognosis, low extracellular matrix expression and reduced YAP activation

FOXP3+ T cells in uterine sarcomas are associated with favorable prognosis, low extracellular matrix expression and reduced YAP activation

Abstract Uterine sarcomas are rare but deadly malignancies without effective treatment. Immunotherapy is a promising new approach to treat these tumors but has shown heterogeneous effects in sarcoma patients. With the goal of identifying key factors for improved patient treatment, we characterized t...

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Autores principales: Okan Gultekin, Jordi Gonzalez-Molina, Elin Hardell, Lidia Moyano-Galceran, Nicholas Mitsios, Jan Mulder, Georgia Kokaraki, Anders Isaksson, Dhifaf Sarhan, Kaisa Lehti, Joseph W. Carlson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Acceso en línea:https://doaj.org/article/eda4826495d543a98d261183c1886ac9
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