Grb2 binding induces phosphorylation-independent activation of Shp2
Lin et al. investigate the interactions between adaptor protein, Grb2, and the ubiquitously expressed protein tyrosine phosphatase, Shp2. They find that monomeric Grb2 can activate Shp2 and its downstream signalling in the absence of up-regulation of receptor tyrosine kinases in response to differen...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/edb9c4facda0446e8198cbaac3dd988c |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!