Reduced risk of Plasmodium vivax malaria in Papua New Guinean children with Southeast Asian ovalocytosis in two cohorts and a case-control study.

Reduced risk of Plasmodium vivax malaria in Papua New Guinean children with Southeast Asian ovalocytosis in two cohorts and a case-control study.

<h4>Background</h4>The erythrocyte polymorphism, Southeast Asian ovalocytosis (SAO) (which results from a 27-base pair deletion in the erythrocyte band 3 gene, SLC4A1Δ27) protects against cerebral malaria caused by Plasmodium falciparum; however, it is unknown whether this polymorphism a...

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Bibliographic Details
Main Authors: Anna Rosanas-Urgell, Enmoore Lin, Laurens Manning, Patricia Rarau, Moses Laman, Nicolas Senn, Brian T Grimberg, Livingstone Tavul, Danielle I Stanisic, Leanne J Robinson, John J Aponte, Elijah Dabod, John C Reeder, Peter Siba, Peter A Zimmerman, Timothy M E Davis, Christopher L King, Pascal Michon, Ivo Mueller
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Online Access:https://doaj.org/article/edb9fbd2367a41d599df991edc0a382c
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