Discontinuous patterns of brain activation in the psychotherapy process of obsessive-compulsive disorder: converging results from repeated FMRI and daily self-reports.

This study investigates neuronal activation patterns during the psychotherapeutic process, assuming that change dynamics undergo critical instabilities and discontinuous transitions. An internet-based system was used to collect daily self-assessments during inpatient therapies. A dynamic complexity...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Günter Schiepek, Igor Tominschek, Stephan Heinzel, Martin Aigner, Markus Dold, Annemarie Unger, Gerhard Lenz, Christian Windischberger, Ewald Moser, Martin Plöderl, Jürgen Lutz, Thomas Meindl, Michael Zaudig, Oliver Pogarell, Susanne Karch
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/edba94e07307438dbfc89ac72c6d36c7
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:edba94e07307438dbfc89ac72c6d36c7
record_format	dspace
spelling	oai:doaj.org-article:edba94e07307438dbfc89ac72c6d36c72021-11-18T08:59:24ZDiscontinuous patterns of brain activation in the psychotherapy process of obsessive-compulsive disorder: converging results from repeated FMRI and daily self-reports.1932-620310.1371/journal.pone.0071863https://doaj.org/article/edba94e07307438dbfc89ac72c6d36c72013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23977168/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203This study investigates neuronal activation patterns during the psychotherapeutic process, assuming that change dynamics undergo critical instabilities and discontinuous transitions. An internet-based system was used to collect daily self-assessments during inpatient therapies. A dynamic complexity measure was applied to the resulting time series. Critical phases of the change process were indicated by the maxima of the varying complexity. Repeated functional magnetic resonance imaging (fMRI) measurements were conducted over the course of the therapy. The study was realized with 9 patients suffering from obsessive-compulsive disorder (subtype: washing/contamination fear) and 9 matched healthy controls. For symptom-provocative stimulation individualized pictures from patients' personal environments were used. The neuronal responses to these disease-specific pictures were compared to the responses during standardized disgust-provoking and neutral pictures. Considerably larger neuronal changes in therapy-relevant brain areas (cingulate cortex/supplementary motor cortex, bilateral dorsolateral prefrontal cortex, bilateral insula, bilateral parietal cortex, cuneus) were observed during critical phases (order transitions), as compared to non-critical phases, and also compared to healthy controls. The data indicate that non-stationary changes play a crucial role in the psychotherapeutic process supporting self-organization and complexity models of therapeutic change.Günter SchiepekIgor TominschekStephan HeinzelMartin AignerMarkus DoldMarkus DoldAnnemarie UngerGerhard LenzChristian WindischbergerEwald MoserMartin PlöderlJürgen LutzThomas MeindlMichael ZaudigOliver PogarellSusanne KarchPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 8, p e71863 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Günter Schiepek Igor Tominschek Stephan Heinzel Martin Aigner Markus Dold Markus Dold Annemarie Unger Gerhard Lenz Christian Windischberger Ewald Moser Martin Plöderl Jürgen Lutz Thomas Meindl Michael Zaudig Oliver Pogarell Susanne Karch Discontinuous patterns of brain activation in the psychotherapy process of obsessive-compulsive disorder: converging results from repeated FMRI and daily self-reports.
description	This study investigates neuronal activation patterns during the psychotherapeutic process, assuming that change dynamics undergo critical instabilities and discontinuous transitions. An internet-based system was used to collect daily self-assessments during inpatient therapies. A dynamic complexity measure was applied to the resulting time series. Critical phases of the change process were indicated by the maxima of the varying complexity. Repeated functional magnetic resonance imaging (fMRI) measurements were conducted over the course of the therapy. The study was realized with 9 patients suffering from obsessive-compulsive disorder (subtype: washing/contamination fear) and 9 matched healthy controls. For symptom-provocative stimulation individualized pictures from patients' personal environments were used. The neuronal responses to these disease-specific pictures were compared to the responses during standardized disgust-provoking and neutral pictures. Considerably larger neuronal changes in therapy-relevant brain areas (cingulate cortex/supplementary motor cortex, bilateral dorsolateral prefrontal cortex, bilateral insula, bilateral parietal cortex, cuneus) were observed during critical phases (order transitions), as compared to non-critical phases, and also compared to healthy controls. The data indicate that non-stationary changes play a crucial role in the psychotherapeutic process supporting self-organization and complexity models of therapeutic change.
format	article
author	Günter Schiepek Igor Tominschek Stephan Heinzel Martin Aigner Markus Dold Markus Dold Annemarie Unger Gerhard Lenz Christian Windischberger Ewald Moser Martin Plöderl Jürgen Lutz Thomas Meindl Michael Zaudig Oliver Pogarell Susanne Karch
author_facet	Günter Schiepek Igor Tominschek Stephan Heinzel Martin Aigner Markus Dold Markus Dold Annemarie Unger Gerhard Lenz Christian Windischberger Ewald Moser Martin Plöderl Jürgen Lutz Thomas Meindl Michael Zaudig Oliver Pogarell Susanne Karch
author_sort	Günter Schiepek
title	Discontinuous patterns of brain activation in the psychotherapy process of obsessive-compulsive disorder: converging results from repeated FMRI and daily self-reports.
title_short	Discontinuous patterns of brain activation in the psychotherapy process of obsessive-compulsive disorder: converging results from repeated FMRI and daily self-reports.
title_full	Discontinuous patterns of brain activation in the psychotherapy process of obsessive-compulsive disorder: converging results from repeated FMRI and daily self-reports.
title_fullStr	Discontinuous patterns of brain activation in the psychotherapy process of obsessive-compulsive disorder: converging results from repeated FMRI and daily self-reports.
title_full_unstemmed	Discontinuous patterns of brain activation in the psychotherapy process of obsessive-compulsive disorder: converging results from repeated FMRI and daily self-reports.
title_sort	discontinuous patterns of brain activation in the psychotherapy process of obsessive-compulsive disorder: converging results from repeated fmri and daily self-reports.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/edba94e07307438dbfc89ac72c6d36c7
work_keys_str_mv	AT gunterschiepek discontinuouspatternsofbrainactivationinthepsychotherapyprocessofobsessivecompulsivedisorderconvergingresultsfromrepeatedfmrianddailyselfreports AT igortominschek discontinuouspatternsofbrainactivationinthepsychotherapyprocessofobsessivecompulsivedisorderconvergingresultsfromrepeatedfmrianddailyselfreports AT stephanheinzel discontinuouspatternsofbrainactivationinthepsychotherapyprocessofobsessivecompulsivedisorderconvergingresultsfromrepeatedfmrianddailyselfreports AT martinaigner discontinuouspatternsofbrainactivationinthepsychotherapyprocessofobsessivecompulsivedisorderconvergingresultsfromrepeatedfmrianddailyselfreports AT markusdold discontinuouspatternsofbrainactivationinthepsychotherapyprocessofobsessivecompulsivedisorderconvergingresultsfromrepeatedfmrianddailyselfreports AT markusdold discontinuouspatternsofbrainactivationinthepsychotherapyprocessofobsessivecompulsivedisorderconvergingresultsfromrepeatedfmrianddailyselfreports AT annemarieunger discontinuouspatternsofbrainactivationinthepsychotherapyprocessofobsessivecompulsivedisorderconvergingresultsfromrepeatedfmrianddailyselfreports AT gerhardlenz discontinuouspatternsofbrainactivationinthepsychotherapyprocessofobsessivecompulsivedisorderconvergingresultsfromrepeatedfmrianddailyselfreports AT christianwindischberger discontinuouspatternsofbrainactivationinthepsychotherapyprocessofobsessivecompulsivedisorderconvergingresultsfromrepeatedfmrianddailyselfreports AT ewaldmoser discontinuouspatternsofbrainactivationinthepsychotherapyprocessofobsessivecompulsivedisorderconvergingresultsfromrepeatedfmrianddailyselfreports AT martinploderl discontinuouspatternsofbrainactivationinthepsychotherapyprocessofobsessivecompulsivedisorderconvergingresultsfromrepeatedfmrianddailyselfreports AT jurgenlutz discontinuouspatternsofbrainactivationinthepsychotherapyprocessofobsessivecompulsivedisorderconvergingresultsfromrepeatedfmrianddailyselfreports AT thomasmeindl discontinuouspatternsofbrainactivationinthepsychotherapyprocessofobsessivecompulsivedisorderconvergingresultsfromrepeatedfmrianddailyselfreports AT michaelzaudig discontinuouspatternsofbrainactivationinthepsychotherapyprocessofobsessivecompulsivedisorderconvergingresultsfromrepeatedfmrianddailyselfreports AT oliverpogarell discontinuouspatternsofbrainactivationinthepsychotherapyprocessofobsessivecompulsivedisorderconvergingresultsfromrepeatedfmrianddailyselfreports AT susannekarch discontinuouspatternsofbrainactivationinthepsychotherapyprocessofobsessivecompulsivedisorderconvergingresultsfromrepeatedfmrianddailyselfreports
_version_	1718421118000300032

Discontinuous patterns of brain activation in the psychotherapy process of obsessive-compulsive disorder: converging results from repeated FMRI and daily self-reports.

Ejemplares similares