Design, development and optimization of sustained release floating, bioadhesive and swellable matrix tablet of ranitidine hydrochloride.
Ranitidine HCl, a selective, competitive histamine H2-receptor antagonist with a short biological half-life, low bioavailability and narrow absorption window, is an ideal candidate for gastro-retentive drug delivery system (GRDDS). Controlled release with an optimum retentive formulation in the uppe...
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Main Authors: | Birhanu Nigusse, Tsige Gebre-Mariam, Anteneh Belete |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2021
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Subjects: | |
Online Access: | https://doaj.org/article/edbfcd5735844e8cbb68d5fb371adbb4 |
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