The RAD51 recombinase protects mitotic chromatin in human cells

RAD51 is a well known player of DNA repair and homologous recombination. Here the authors reveal a function for RAD51 in protecting under-replicated DNA in mitotic human cells, promoting mitotic DNA synthesis (MiDAS) and successful chromosome segregation.

Guardado en:

Detalles Bibliográficos
Autores principales:	Isabel E. Wassing, Emily Graham, Xanita Saayman, Lucia Rampazzo, Christine Ralf, Andrew Bassett, Fumiko Esashi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/edc529610cfe4e3884a66076ba7caeea
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:edc529610cfe4e3884a66076ba7caeea
record_format	dspace
spelling	oai:doaj.org-article:edc529610cfe4e3884a66076ba7caeea2021-12-02T17:42:05ZThe RAD51 recombinase protects mitotic chromatin in human cells10.1038/s41467-021-25643-y2041-1723https://doaj.org/article/edc529610cfe4e3884a66076ba7caeea2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25643-yhttps://doaj.org/toc/2041-1723RAD51 is a well known player of DNA repair and homologous recombination. Here the authors reveal a function for RAD51 in protecting under-replicated DNA in mitotic human cells, promoting mitotic DNA synthesis (MiDAS) and successful chromosome segregation.Isabel E. WassingEmily GrahamXanita SaaymanLucia RampazzoChristine RalfAndrew BassettFumiko EsashiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Isabel E. Wassing Emily Graham Xanita Saayman Lucia Rampazzo Christine Ralf Andrew Bassett Fumiko Esashi The RAD51 recombinase protects mitotic chromatin in human cells
description	RAD51 is a well known player of DNA repair and homologous recombination. Here the authors reveal a function for RAD51 in protecting under-replicated DNA in mitotic human cells, promoting mitotic DNA synthesis (MiDAS) and successful chromosome segregation.
format	article
author	Isabel E. Wassing Emily Graham Xanita Saayman Lucia Rampazzo Christine Ralf Andrew Bassett Fumiko Esashi
author_facet	Isabel E. Wassing Emily Graham Xanita Saayman Lucia Rampazzo Christine Ralf Andrew Bassett Fumiko Esashi
author_sort	Isabel E. Wassing
title	The RAD51 recombinase protects mitotic chromatin in human cells
title_short	The RAD51 recombinase protects mitotic chromatin in human cells
title_full	The RAD51 recombinase protects mitotic chromatin in human cells
title_fullStr	The RAD51 recombinase protects mitotic chromatin in human cells
title_full_unstemmed	The RAD51 recombinase protects mitotic chromatin in human cells
title_sort	rad51 recombinase protects mitotic chromatin in human cells
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/edc529610cfe4e3884a66076ba7caeea
work_keys_str_mv	AT isabelewassing therad51recombinaseprotectsmitoticchromatininhumancells AT emilygraham therad51recombinaseprotectsmitoticchromatininhumancells AT xanitasaayman therad51recombinaseprotectsmitoticchromatininhumancells AT luciarampazzo therad51recombinaseprotectsmitoticchromatininhumancells AT christineralf therad51recombinaseprotectsmitoticchromatininhumancells AT andrewbassett therad51recombinaseprotectsmitoticchromatininhumancells AT fumikoesashi therad51recombinaseprotectsmitoticchromatininhumancells AT isabelewassing rad51recombinaseprotectsmitoticchromatininhumancells AT emilygraham rad51recombinaseprotectsmitoticchromatininhumancells AT xanitasaayman rad51recombinaseprotectsmitoticchromatininhumancells AT luciarampazzo rad51recombinaseprotectsmitoticchromatininhumancells AT christineralf rad51recombinaseprotectsmitoticchromatininhumancells AT andrewbassett rad51recombinaseprotectsmitoticchromatininhumancells AT fumikoesashi rad51recombinaseprotectsmitoticchromatininhumancells
_version_	1718379679419727872

The RAD51 recombinase protects mitotic chromatin in human cells

Ejemplares similares