Fermented Corn–Soybean Meal Mixed Feed Modulates Intestinal Morphology, Barrier Functions and Cecal Microbiota in Laying Hens

This study aimed to evaluate the effects of fermented corn–soybean meal mixed feed on intestinal barrier function and cecal microbiota in laying hens. A total of 360 Jingfen No.6 laying hens (22 wk-old) were assigned to 4 dietary treatments, which were offered basal diets (without antibiotics) conta...

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Autores principales:	Yinglu Liu, Jia Feng, Yamin Wang, Jing Lv, Jinghe Li, Lijuan Guo, Yuna Min
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	fermented feed laying hen cecal microbiota gut health Veterinary medicine SF600-1100 Zoology QL1-991
Acceso en línea:	https://doaj.org/article/edc723c9f5394b13b0672899b44df5d9
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spelling	oai:doaj.org-article:edc723c9f5394b13b0672899b44df5d92021-11-25T16:14:18ZFermented Corn–Soybean Meal Mixed Feed Modulates Intestinal Morphology, Barrier Functions and Cecal Microbiota in Laying Hens10.3390/ani111130592076-2615https://doaj.org/article/edc723c9f5394b13b0672899b44df5d92021-10-01T00:00:00Zhttps://www.mdpi.com/2076-2615/11/11/3059https://doaj.org/toc/2076-2615This study aimed to evaluate the effects of fermented corn–soybean meal mixed feed on intestinal barrier function and cecal microbiota in laying hens. A total of 360 Jingfen No.6 laying hens (22 wk-old) were assigned to 4 dietary treatments, which were offered basal diets (without antibiotics) containing 0, 4, 6 and 8% of fermented mixed feed respectively. The results showed that the pH value and anti-nutritional factor concentrations in fermented mixed feed were lower than those in unfermented feed (<i>p</i> < 0.05). Moreover, fermentation in the feed significantly increased the crude protein content (<i>p</i> < 0.05). Supplementation with fermented feed significantly reduced the crypt depth and increased the villi height:crypt depth ratio of duodenum and jejunum (<i>p</i> < 0.05). Meanwhile, fermented feed increased the secretory immunoglobulin A content and MUC2 mRNA expression of jejunum (<i>p</i> < 0.05). These beneficial effects were exhibited at the addition level ≥6% and microbial composition of caeca in the control, and so 6% fermented feed groups were analyzed. The structure of the gut microbiota was remarkably altered by additions, characterized by increased abundances of some health-promoting bacteria, such as <i>Parasutterella</i>, <i>Butyricicoccus</i> and <i>Erysipelotrichaceae</i> (<i>p</i> < 0.05). In summary, fermented mixed feed modulated cecal flora, subsequently contributing to improvements in intestinal morphology and barrier functions in laying hens.Yinglu LiuJia FengYamin WangJing LvJinghe LiLijuan GuoYuna MinMDPI AGarticlefermented feedlaying hencecal microbiotagut healthVeterinary medicineSF600-1100ZoologyQL1-991ENAnimals, Vol 11, Iss 3059, p 3059 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	fermented feed laying hen cecal microbiota gut health Veterinary medicine SF600-1100 Zoology QL1-991
spellingShingle	fermented feed laying hen cecal microbiota gut health Veterinary medicine SF600-1100 Zoology QL1-991 Yinglu Liu Jia Feng Yamin Wang Jing Lv Jinghe Li Lijuan Guo Yuna Min Fermented Corn–Soybean Meal Mixed Feed Modulates Intestinal Morphology, Barrier Functions and Cecal Microbiota in Laying Hens
description	This study aimed to evaluate the effects of fermented corn–soybean meal mixed feed on intestinal barrier function and cecal microbiota in laying hens. A total of 360 Jingfen No.6 laying hens (22 wk-old) were assigned to 4 dietary treatments, which were offered basal diets (without antibiotics) containing 0, 4, 6 and 8% of fermented mixed feed respectively. The results showed that the pH value and anti-nutritional factor concentrations in fermented mixed feed were lower than those in unfermented feed (<i>p</i> < 0.05). Moreover, fermentation in the feed significantly increased the crude protein content (<i>p</i> < 0.05). Supplementation with fermented feed significantly reduced the crypt depth and increased the villi height:crypt depth ratio of duodenum and jejunum (<i>p</i> < 0.05). Meanwhile, fermented feed increased the secretory immunoglobulin A content and MUC2 mRNA expression of jejunum (<i>p</i> < 0.05). These beneficial effects were exhibited at the addition level ≥6% and microbial composition of caeca in the control, and so 6% fermented feed groups were analyzed. The structure of the gut microbiota was remarkably altered by additions, characterized by increased abundances of some health-promoting bacteria, such as <i>Parasutterella</i>, <i>Butyricicoccus</i> and <i>Erysipelotrichaceae</i> (<i>p</i> < 0.05). In summary, fermented mixed feed modulated cecal flora, subsequently contributing to improvements in intestinal morphology and barrier functions in laying hens.
format	article
author	Yinglu Liu Jia Feng Yamin Wang Jing Lv Jinghe Li Lijuan Guo Yuna Min
author_facet	Yinglu Liu Jia Feng Yamin Wang Jing Lv Jinghe Li Lijuan Guo Yuna Min
author_sort	Yinglu Liu
title	Fermented Corn–Soybean Meal Mixed Feed Modulates Intestinal Morphology, Barrier Functions and Cecal Microbiota in Laying Hens
title_short	Fermented Corn–Soybean Meal Mixed Feed Modulates Intestinal Morphology, Barrier Functions and Cecal Microbiota in Laying Hens
title_full	Fermented Corn–Soybean Meal Mixed Feed Modulates Intestinal Morphology, Barrier Functions and Cecal Microbiota in Laying Hens
title_fullStr	Fermented Corn–Soybean Meal Mixed Feed Modulates Intestinal Morphology, Barrier Functions and Cecal Microbiota in Laying Hens
title_full_unstemmed	Fermented Corn–Soybean Meal Mixed Feed Modulates Intestinal Morphology, Barrier Functions and Cecal Microbiota in Laying Hens
title_sort	fermented corn–soybean meal mixed feed modulates intestinal morphology, barrier functions and cecal microbiota in laying hens
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/edc723c9f5394b13b0672899b44df5d9
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Fermented Corn–Soybean Meal Mixed Feed Modulates Intestinal Morphology, Barrier Functions and Cecal Microbiota in Laying Hens

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