NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis
The authors use an integrative clustering approach to identify two laryngeal cancer clusters with distinct prognosis and show that mutations damaging the NSD1 and NSD2 methyltransferases segregate to the cluster with favorable prognosis, and independently predict longer survival in patients with lar...
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Autores principales: | Suraj Peri, Evgeny Izumchenko, Adrian D. Schubert, Michael J. Slifker, Karen Ruth, Ilya G. Serebriiskii, Theresa Guo, Barbara A. Burtness, Ranee Mehra, Eric A. Ross, David Sidransky, Erica A. Golemis |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/eddde834c4f34581ae63259cb1d66acc |
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