Food for song: expression of c-Fos and ZENK in the zebra finch song nuclei during food aversion learning.

<h4>Background</h4>Specialized neural pathways, the song system, are required for acquiring, producing, and perceiving learned avian vocalizations. Birds that do not learn to produce their vocalizations lack telencephalic song system components. It is not known whether the song system fo...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Kirill Tokarev, Anna Tiunova, Constance Scharff, Konstantin Anokhin
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2011
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/eddfada5ef674412a4d8f93b0c22dbf7
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:eddfada5ef674412a4d8f93b0c22dbf7
record_format	dspace
spelling	oai:doaj.org-article:eddfada5ef674412a4d8f93b0c22dbf72021-11-18T06:52:17ZFood for song: expression of c-Fos and ZENK in the zebra finch song nuclei during food aversion learning.1932-620310.1371/journal.pone.0021157https://doaj.org/article/eddfada5ef674412a4d8f93b0c22dbf72011-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21695176/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Specialized neural pathways, the song system, are required for acquiring, producing, and perceiving learned avian vocalizations. Birds that do not learn to produce their vocalizations lack telencephalic song system components. It is not known whether the song system forebrain regions are exclusively evolved for song or whether they also process information not related to song that might reflect their 'evolutionary history'.<h4>Methodology/principal findings</h4>To address this question we monitored the induction of two immediate-early genes (IEGs) c-Fos and ZENK in various regions of the song system in zebra finches (Taeniopygia guttata) in response to an aversive food learning paradigm; this involves the association of a food item with a noxious stimulus that affects the oropharyngeal-esophageal cavity and tongue, causing subsequent avoidance of that food item. The motor response results in beak and head movements but not vocalizations. IEGs have been extensively used to map neuro-molecular correlates of song motor production and auditory processing. As previously reported, neurons in two pallial vocal motor regions, HVC and RA, expressed IEGs after singing. Surprisingly, c-Fos was induced equivalently also after food aversion learning in the absence of singing. The density of c-Fos positive neurons was significantly higher than that of birds in control conditions. This was not the case in two other pallial song nuclei important for vocal plasticity, LMAN and Area X, although singing did induce IEGs in these structures, as reported previously.<h4>Conclusions/significance</h4>Our results are consistent with the possibility that some of the song nuclei may participate in non-vocal learning and the populations of neurons involved in the two tasks show partial overlap. These findings underscore the previously advanced notion that the specialized forebrain pre-motor nuclei controlling song evolved from circuits involved in behaviors related to feeding.Kirill TokarevAnna TiunovaConstance ScharffKonstantin AnokhinPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 6, Iss 6, p e21157 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kirill Tokarev Anna Tiunova Constance Scharff Konstantin Anokhin Food for song: expression of c-Fos and ZENK in the zebra finch song nuclei during food aversion learning.
description	<h4>Background</h4>Specialized neural pathways, the song system, are required for acquiring, producing, and perceiving learned avian vocalizations. Birds that do not learn to produce their vocalizations lack telencephalic song system components. It is not known whether the song system forebrain regions are exclusively evolved for song or whether they also process information not related to song that might reflect their 'evolutionary history'.<h4>Methodology/principal findings</h4>To address this question we monitored the induction of two immediate-early genes (IEGs) c-Fos and ZENK in various regions of the song system in zebra finches (Taeniopygia guttata) in response to an aversive food learning paradigm; this involves the association of a food item with a noxious stimulus that affects the oropharyngeal-esophageal cavity and tongue, causing subsequent avoidance of that food item. The motor response results in beak and head movements but not vocalizations. IEGs have been extensively used to map neuro-molecular correlates of song motor production and auditory processing. As previously reported, neurons in two pallial vocal motor regions, HVC and RA, expressed IEGs after singing. Surprisingly, c-Fos was induced equivalently also after food aversion learning in the absence of singing. The density of c-Fos positive neurons was significantly higher than that of birds in control conditions. This was not the case in two other pallial song nuclei important for vocal plasticity, LMAN and Area X, although singing did induce IEGs in these structures, as reported previously.<h4>Conclusions/significance</h4>Our results are consistent with the possibility that some of the song nuclei may participate in non-vocal learning and the populations of neurons involved in the two tasks show partial overlap. These findings underscore the previously advanced notion that the specialized forebrain pre-motor nuclei controlling song evolved from circuits involved in behaviors related to feeding.
format	article
author	Kirill Tokarev Anna Tiunova Constance Scharff Konstantin Anokhin
author_facet	Kirill Tokarev Anna Tiunova Constance Scharff Konstantin Anokhin
author_sort	Kirill Tokarev
title	Food for song: expression of c-Fos and ZENK in the zebra finch song nuclei during food aversion learning.
title_short	Food for song: expression of c-Fos and ZENK in the zebra finch song nuclei during food aversion learning.
title_full	Food for song: expression of c-Fos and ZENK in the zebra finch song nuclei during food aversion learning.
title_fullStr	Food for song: expression of c-Fos and ZENK in the zebra finch song nuclei during food aversion learning.
title_full_unstemmed	Food for song: expression of c-Fos and ZENK in the zebra finch song nuclei during food aversion learning.
title_sort	food for song: expression of c-fos and zenk in the zebra finch song nuclei during food aversion learning.
publisher	Public Library of Science (PLoS)
publishDate	2011
url	https://doaj.org/article/eddfada5ef674412a4d8f93b0c22dbf7
work_keys_str_mv	AT kirilltokarev foodforsongexpressionofcfosandzenkinthezebrafinchsongnucleiduringfoodaversionlearning AT annatiunova foodforsongexpressionofcfosandzenkinthezebrafinchsongnucleiduringfoodaversionlearning AT constancescharff foodforsongexpressionofcfosandzenkinthezebrafinchsongnucleiduringfoodaversionlearning AT konstantinanokhin foodforsongexpressionofcfosandzenkinthezebrafinchsongnucleiduringfoodaversionlearning
_version_	1718424327287734272

Food for song: expression of c-Fos and ZENK in the zebra finch song nuclei during food aversion learning.

Ejemplares similares