Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity

Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity

Abstract It was previously reported that mRNA expression levels in the prefrontal cortex at old age start to resemble pre-adult levels. Such expression reversals could imply loss of cellular identity in the aging brain, and provide a link between aging-related molecular changes and functional declin...

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Autores principales: Handan Melike Dönertaş, Hamit İzgi, Altuğ Kamacıoğlu, Zhisong He, Philipp Khaitovich, Mehmet Somel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/ededa3881d4b43a9b6f96ce5433f351a
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