Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity
Abstract It was previously reported that mRNA expression levels in the prefrontal cortex at old age start to resemble pre-adult levels. Such expression reversals could imply loss of cellular identity in the aging brain, and provide a link between aging-related molecular changes and functional declin...
Enregistré dans:
Auteurs principaux: | Handan Melike Dönertaş, Hamit İzgi, Altuğ Kamacıoğlu, Zhisong He, Philipp Khaitovich, Mehmet Somel |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/ededa3881d4b43a9b6f96ce5433f351a |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Mechanisms of dietary response in mice and primates: a role for EGR1 in regulating the reaction to human-specific nutritional content.
par: Kai Weng, et autres
Publié: (2012) -
International Conference: Fingerprinting the Iron Age: Approaches to identity in the European Iron Age
par: Ivan Vranić, et autres
Publié: (2016) -
ACTİVE AGİNG POLİCY: THE ACTİVE AGİNG PERCEPTİONS OF ELDERLY PEOPLE WHO STAYED WİTH THEİR FAMİLY SUPPORTED BY HOME CARE AİD AND WHO STAYED AT NURSİNG HOMES
par: Yusuf GENÇ, et autres
Publié: (2019) -
Aging, estrogen loss and epoxyeicosatrienoic acids (EETs).
par: Alison R Lee, et autres
Publié: (2013) -
Cellular senescence drives age-dependent hepatic steatosis
par: Mikolaj Ogrodnik, et autres
Publié: (2017)