Post-Hypoxic Cells Promote Metastatic Recurrence after Chemotherapy Treatment in TNBC
Hypoxia occurs in 90% of solid tumors and is associated with treatment failure, relapse, and mortality. HIF-1α signaling promotes resistance to chemotherapy in cancer cell lines and murine models via multiple mechanisms including the enrichment of breast cancer stem cells (BCSCs). In this work, we u...
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| Auteurs principaux: | , , , , |
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| Format: | article |
| Langue: | EN |
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MDPI AG
2021
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| Accès en ligne: | https://doaj.org/article/edee0cfbbc51437ca7bef0f721d1a1a4 |
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