Post-Hypoxic Cells Promote Metastatic Recurrence after Chemotherapy Treatment in TNBC

Hypoxia occurs in 90% of solid tumors and is associated with treatment failure, relapse, and mortality. HIF-1α signaling promotes resistance to chemotherapy in cancer cell lines and murine models via multiple mechanisms including the enrichment of breast cancer stem cells (BCSCs). In this work, we u...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Inês Godet, Mahelet Mamo, Andrea Thurnheer, D. Marc Rosen, Daniele M. Gilkes
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
Accès en ligne:https://doaj.org/article/edee0cfbbc51437ca7bef0f721d1a1a4
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!