Seasonal Urinary Levels of Glyphosate in Children From Agricultural Communities

Background Glyphosate is one of the most commonly used pesticides in agricultural activities worldwide. For the last 20 years, its use has increased rapidly becoming a public health concern. The IARC classified glyphosate as probably carcinogenic; however, the reported evidence is not enough to esta...

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Autores principales:	Felipe Lozano-Kasten MD, PhD, Erick Sierra-Diaz MD, PhD, Humberto Gonzalez Chavez PhD, Alejandro Aarón Peregrina Lucano PhD, Rosa Cremades, Elena Sandoval Pinto PhD
Formato:	article
Lenguaje:	EN
Publicado:	SAGE Publishing 2021
Materias:	Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/edefa43858524a43ae54a947f8b15d48
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spelling	oai:doaj.org-article:edefa43858524a43ae54a947f8b15d482021-11-06T22:03:35ZSeasonal Urinary Levels of Glyphosate in Children From Agricultural Communities1559-325810.1177/15593258211053184https://doaj.org/article/edefa43858524a43ae54a947f8b15d482021-10-01T00:00:00Zhttps://doi.org/10.1177/15593258211053184https://doaj.org/toc/1559-3258Background Glyphosate is one of the most commonly used pesticides in agricultural activities worldwide. For the last 20 years, its use has increased rapidly becoming a public health concern. The IARC classified glyphosate as probably carcinogenic; however, the reported evidence is not enough to establish a statement. Objective This work aimed to measure glyphosate levels in the urine of children from a single rural community in an endemic region of chronic kidney disease and malnutrition. Methods A cross-sectional study was carried out in a rural community in western Mexico. The study included 95 children between the ages of 6 and 16. A urine sample (first-morning spot) was obtained from children and processed to measure glyphosate levels using high-performance liquid chromatography coupled with tandem mass spectrometry. Results All samples tested positive for glyphosate levels. Urine glyphosate levels were related to the season and the age of the children. Conclusion Glyphosate is present in children of all ages in the community even if they were not in direct contact with it. No toxicity cases were reported, nor were there other health problems related to glyphosate. However, more long-term studies should be done that provide a statement regarding the harmful effects that glyphosate has on public health.Felipe Lozano-Kasten MD, PhDErick Sierra-Diaz MD, PhDHumberto Gonzalez Chavez PhDAlejandro Aarón Peregrina Lucano PhDRosa CremadesElena Sandoval Pinto PhDSAGE PublishingarticleTherapeutics. PharmacologyRM1-950ENDose-Response, Vol 19 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Therapeutics. Pharmacology RM1-950
spellingShingle	Therapeutics. Pharmacology RM1-950 Felipe Lozano-Kasten MD, PhD Erick Sierra-Diaz MD, PhD Humberto Gonzalez Chavez PhD Alejandro Aarón Peregrina Lucano PhD Rosa Cremades Elena Sandoval Pinto PhD Seasonal Urinary Levels of Glyphosate in Children From Agricultural Communities
description	Background Glyphosate is one of the most commonly used pesticides in agricultural activities worldwide. For the last 20 years, its use has increased rapidly becoming a public health concern. The IARC classified glyphosate as probably carcinogenic; however, the reported evidence is not enough to establish a statement. Objective This work aimed to measure glyphosate levels in the urine of children from a single rural community in an endemic region of chronic kidney disease and malnutrition. Methods A cross-sectional study was carried out in a rural community in western Mexico. The study included 95 children between the ages of 6 and 16. A urine sample (first-morning spot) was obtained from children and processed to measure glyphosate levels using high-performance liquid chromatography coupled with tandem mass spectrometry. Results All samples tested positive for glyphosate levels. Urine glyphosate levels were related to the season and the age of the children. Conclusion Glyphosate is present in children of all ages in the community even if they were not in direct contact with it. No toxicity cases were reported, nor were there other health problems related to glyphosate. However, more long-term studies should be done that provide a statement regarding the harmful effects that glyphosate has on public health.
format	article
author	Felipe Lozano-Kasten MD, PhD Erick Sierra-Diaz MD, PhD Humberto Gonzalez Chavez PhD Alejandro Aarón Peregrina Lucano PhD Rosa Cremades Elena Sandoval Pinto PhD
author_facet	Felipe Lozano-Kasten MD, PhD Erick Sierra-Diaz MD, PhD Humberto Gonzalez Chavez PhD Alejandro Aarón Peregrina Lucano PhD Rosa Cremades Elena Sandoval Pinto PhD
author_sort	Felipe Lozano-Kasten MD, PhD
title	Seasonal Urinary Levels of Glyphosate in Children From Agricultural Communities
title_short	Seasonal Urinary Levels of Glyphosate in Children From Agricultural Communities
title_full	Seasonal Urinary Levels of Glyphosate in Children From Agricultural Communities
title_fullStr	Seasonal Urinary Levels of Glyphosate in Children From Agricultural Communities
title_full_unstemmed	Seasonal Urinary Levels of Glyphosate in Children From Agricultural Communities
title_sort	seasonal urinary levels of glyphosate in children from agricultural communities
publisher	SAGE Publishing
publishDate	2021
url	https://doaj.org/article/edefa43858524a43ae54a947f8b15d48
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Seasonal Urinary Levels of Glyphosate in Children From Agricultural Communities

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