Connected drug delivery devices to complement drug treatments: potential to facilitate disease management in home setting

Beate Bittner,1 Chantal Schmit Chiesi,1 Saifuddin Kharawala,2 Gavneet Kaur,2 Johannes Schmidt1 1Product Optimization, Global Product Strategy, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland; 2Bridge Medical Consulting Ltd, Richmond, London, TW9 2SS, UK Abstract: Connected drug delivery devices ar...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Bittner B, Schmit Chiesi C, Kharawala S, Kaur G, Schmidt J
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Home-administration Self-administration Connected drug delivery device Adherence Patient-reported outcomes Real-world evidence Medical technology R855-855.5
Acceso en línea:	https://doaj.org/article/edfb89a5e4654b08ae4aedd6d243806e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:edfb89a5e4654b08ae4aedd6d243806e
record_format	dspace
spelling	oai:doaj.org-article:edfb89a5e4654b08ae4aedd6d243806e2021-12-02T00:46:37ZConnected drug delivery devices to complement drug treatments: potential to facilitate disease management in home setting1179-1470https://doaj.org/article/edfb89a5e4654b08ae4aedd6d243806e2019-03-01T00:00:00Zhttps://www.dovepress.com/connected-drug-delivery-devices-to-complement-drug-treatments-potentia-peer-reviewed-article-MDERhttps://doaj.org/toc/1179-1470Beate Bittner,1 Chantal Schmit Chiesi,1 Saifuddin Kharawala,2 Gavneet Kaur,2 Johannes Schmidt1 1Product Optimization, Global Product Strategy, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland; 2Bridge Medical Consulting Ltd, Richmond, London, TW9 2SS, UK Abstract: Connected drug delivery devices are increasingly being developed to support patient supervision and counseling in home setting. Features may include dosing reminders, adherence trackers, tools for patient education, and patient diaries to collect patient-reported outcomes, as well as monitoring tools with interfaces between patients and health care professionals (HCPs). Five connected devices have been selected as the basis for a review of the clinical evidence concerning the impact of electronic tools on treatment adherence and efficacy outcomes. Disease areas covered include multiple sclerosis, diabetes, hypertension, liver and renal transplant recipients, tuberculosis, hepatitis C, clinically isolated syndrome, asthma, and COPD. From studies comparing the use of electronic feedback tools to standard of care, there is an initial evidence for a higher adherence to treatment and better outcomes among patients who use the electronic tools. To substantiate the assumption that connected devices can improve adherence in an outpatient setting over a prolonged period of time, further data from controlled randomized studies are required. Key barriers to the broader adoption of connected devices include data privacy laws that may prevent data sharing with HCPs in some countries, as well as the need to demonstrate that the tools are consistently used and generate a high-quality and reproducible database. If these challenges can be addressed in a way that is agreeable to all stakeholders, it is expected that the future value of connected devices will be to 1) facilitate and improve patient involvement in disease management in a flexible care setting, 2) enable early treatment decisions, and 3) complement value-based reimbursement models. Keywords: home-administration, self-administration, connected drug delivery device, adherence, patient-reported outcomes, real-world evidenceBittner BSchmit Chiesi CKharawala SKaur GSchmidt JDove Medical PressarticleHome-administrationSelf-administrationConnected drug delivery deviceAdherencePatient-reported outcomesReal-world evidenceMedical technologyR855-855.5ENMedical Devices: Evidence and Research, Vol Volume 12, Pp 101-127 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Home-administration Self-administration Connected drug delivery device Adherence Patient-reported outcomes Real-world evidence Medical technology R855-855.5
spellingShingle	Home-administration Self-administration Connected drug delivery device Adherence Patient-reported outcomes Real-world evidence Medical technology R855-855.5 Bittner B Schmit Chiesi C Kharawala S Kaur G Schmidt J Connected drug delivery devices to complement drug treatments: potential to facilitate disease management in home setting
description	Beate Bittner,1 Chantal Schmit Chiesi,1 Saifuddin Kharawala,2 Gavneet Kaur,2 Johannes Schmidt1 1Product Optimization, Global Product Strategy, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland; 2Bridge Medical Consulting Ltd, Richmond, London, TW9 2SS, UK Abstract: Connected drug delivery devices are increasingly being developed to support patient supervision and counseling in home setting. Features may include dosing reminders, adherence trackers, tools for patient education, and patient diaries to collect patient-reported outcomes, as well as monitoring tools with interfaces between patients and health care professionals (HCPs). Five connected devices have been selected as the basis for a review of the clinical evidence concerning the impact of electronic tools on treatment adherence and efficacy outcomes. Disease areas covered include multiple sclerosis, diabetes, hypertension, liver and renal transplant recipients, tuberculosis, hepatitis C, clinically isolated syndrome, asthma, and COPD. From studies comparing the use of electronic feedback tools to standard of care, there is an initial evidence for a higher adherence to treatment and better outcomes among patients who use the electronic tools. To substantiate the assumption that connected devices can improve adherence in an outpatient setting over a prolonged period of time, further data from controlled randomized studies are required. Key barriers to the broader adoption of connected devices include data privacy laws that may prevent data sharing with HCPs in some countries, as well as the need to demonstrate that the tools are consistently used and generate a high-quality and reproducible database. If these challenges can be addressed in a way that is agreeable to all stakeholders, it is expected that the future value of connected devices will be to 1) facilitate and improve patient involvement in disease management in a flexible care setting, 2) enable early treatment decisions, and 3) complement value-based reimbursement models. Keywords: home-administration, self-administration, connected drug delivery device, adherence, patient-reported outcomes, real-world evidence
format	article
author	Bittner B Schmit Chiesi C Kharawala S Kaur G Schmidt J
author_facet	Bittner B Schmit Chiesi C Kharawala S Kaur G Schmidt J
author_sort	Bittner B
title	Connected drug delivery devices to complement drug treatments: potential to facilitate disease management in home setting
title_short	Connected drug delivery devices to complement drug treatments: potential to facilitate disease management in home setting
title_full	Connected drug delivery devices to complement drug treatments: potential to facilitate disease management in home setting
title_fullStr	Connected drug delivery devices to complement drug treatments: potential to facilitate disease management in home setting
title_full_unstemmed	Connected drug delivery devices to complement drug treatments: potential to facilitate disease management in home setting
title_sort	connected drug delivery devices to complement drug treatments: potential to facilitate disease management in home setting
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/edfb89a5e4654b08ae4aedd6d243806e
work_keys_str_mv	AT bittnerb connecteddrugdeliverydevicestocomplementdrugtreatmentspotentialtofacilitatediseasemanagementinhomesetting AT schmitchiesic connecteddrugdeliverydevicestocomplementdrugtreatmentspotentialtofacilitatediseasemanagementinhomesetting AT kharawalas connecteddrugdeliverydevicestocomplementdrugtreatmentspotentialtofacilitatediseasemanagementinhomesetting AT kaurg connecteddrugdeliverydevicestocomplementdrugtreatmentspotentialtofacilitatediseasemanagementinhomesetting AT schmidtj connecteddrugdeliverydevicestocomplementdrugtreatmentspotentialtofacilitatediseasemanagementinhomesetting
_version_	1718403531621269504

Connected drug delivery devices to complement drug treatments: potential to facilitate disease management in home setting

Ejemplares similares