The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs

The human RNA exosome contains a nuclear co-factor MTR4, which unwinds structural RNAs and recruits adaptors for different RNA processing and decay pathways. Here the authors uncover new variations of the arch-interacting motif (AIM) in NVL and ZCCHC8 and characterise their interaction with MTR4.

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Autores principales:	Mahesh Lingaraju, Dennis Johnsen, Andreas Schlundt, Lukas M. Langer, Jérôme Basquin, Michael Sattler, Torben Heick Jensen, Sebastian Falk, Elena Conti
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/edfdcecc250a496aa3a1605e5941f2d9
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spelling	oai:doaj.org-article:edfdcecc250a496aa3a1605e5941f2d92021-12-02T16:58:26ZThe MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs10.1038/s41467-019-11339-x2041-1723https://doaj.org/article/edfdcecc250a496aa3a1605e5941f2d92019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11339-xhttps://doaj.org/toc/2041-1723The human RNA exosome contains a nuclear co-factor MTR4, which unwinds structural RNAs and recruits adaptors for different RNA processing and decay pathways. Here the authors uncover new variations of the arch-interacting motif (AIM) in NVL and ZCCHC8 and characterise their interaction with MTR4.Mahesh LingarajuDennis JohnsenAndreas SchlundtLukas M. LangerJérôme BasquinMichael SattlerTorben Heick JensenSebastian FalkElena ContiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mahesh Lingaraju Dennis Johnsen Andreas Schlundt Lukas M. Langer Jérôme Basquin Michael Sattler Torben Heick Jensen Sebastian Falk Elena Conti The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs
description	The human RNA exosome contains a nuclear co-factor MTR4, which unwinds structural RNAs and recruits adaptors for different RNA processing and decay pathways. Here the authors uncover new variations of the arch-interacting motif (AIM) in NVL and ZCCHC8 and characterise their interaction with MTR4.
format	article
author	Mahesh Lingaraju Dennis Johnsen Andreas Schlundt Lukas M. Langer Jérôme Basquin Michael Sattler Torben Heick Jensen Sebastian Falk Elena Conti
author_facet	Mahesh Lingaraju Dennis Johnsen Andreas Schlundt Lukas M. Langer Jérôme Basquin Michael Sattler Torben Heick Jensen Sebastian Falk Elena Conti
author_sort	Mahesh Lingaraju
title	The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs
title_short	The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs
title_full	The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs
title_fullStr	The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs
title_full_unstemmed	The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs
title_sort	mtr4 helicase recruits nuclear adaptors of the human rna exosome using distinct arch-interacting motifs
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/edfdcecc250a496aa3a1605e5941f2d9
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The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs

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