Comprehensive omic characterization of breast cancer in Mexican-Hispanic women

Cancers in different populations have been shown to be genetically distinct. Here, the authors sequence breast cancers from Mexican-Hispanic patients and find that these patients have a higher percentage of Akt1 mutations compared to Caucasian and Asian populations, suggesting these are clinically a...

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Autores principales: Sandra L. Romero-Cordoba, Ivan Salido-Guadarrama, Rosa Rebollar-Vega, Veronica Bautista-Piña, Carlos Dominguez-Reyes, Alberto Tenorio-Torres, Felipe Villegas-Carlos, Juan C. Fernández-López, Laura Uribe-Figueroa, Luis Alfaro-Ruiz, Alfredo Hidalgo-Miranda
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ee18d53057ea47c8996ebd5a4ca3bc1a
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spelling oai:doaj.org-article:ee18d53057ea47c8996ebd5a4ca3bc1a2021-12-02T14:30:27ZComprehensive omic characterization of breast cancer in Mexican-Hispanic women10.1038/s41467-021-22478-52041-1723https://doaj.org/article/ee18d53057ea47c8996ebd5a4ca3bc1a2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22478-5https://doaj.org/toc/2041-1723Cancers in different populations have been shown to be genetically distinct. Here, the authors sequence breast cancers from Mexican-Hispanic patients and find that these patients have a higher percentage of Akt1 mutations compared to Caucasian and Asian populations, suggesting these are clinically actionable.Sandra L. Romero-CordobaIvan Salido-GuadarramaRosa Rebollar-VegaVeronica Bautista-PiñaCarlos Dominguez-ReyesAlberto Tenorio-TorresFelipe Villegas-CarlosJuan C. Fernández-LópezLaura Uribe-FigueroaLuis Alfaro-RuizAlfredo Hidalgo-MirandaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sandra L. Romero-Cordoba
Ivan Salido-Guadarrama
Rosa Rebollar-Vega
Veronica Bautista-Piña
Carlos Dominguez-Reyes
Alberto Tenorio-Torres
Felipe Villegas-Carlos
Juan C. Fernández-López
Laura Uribe-Figueroa
Luis Alfaro-Ruiz
Alfredo Hidalgo-Miranda
Comprehensive omic characterization of breast cancer in Mexican-Hispanic women
description Cancers in different populations have been shown to be genetically distinct. Here, the authors sequence breast cancers from Mexican-Hispanic patients and find that these patients have a higher percentage of Akt1 mutations compared to Caucasian and Asian populations, suggesting these are clinically actionable.
format article
author Sandra L. Romero-Cordoba
Ivan Salido-Guadarrama
Rosa Rebollar-Vega
Veronica Bautista-Piña
Carlos Dominguez-Reyes
Alberto Tenorio-Torres
Felipe Villegas-Carlos
Juan C. Fernández-López
Laura Uribe-Figueroa
Luis Alfaro-Ruiz
Alfredo Hidalgo-Miranda
author_facet Sandra L. Romero-Cordoba
Ivan Salido-Guadarrama
Rosa Rebollar-Vega
Veronica Bautista-Piña
Carlos Dominguez-Reyes
Alberto Tenorio-Torres
Felipe Villegas-Carlos
Juan C. Fernández-López
Laura Uribe-Figueroa
Luis Alfaro-Ruiz
Alfredo Hidalgo-Miranda
author_sort Sandra L. Romero-Cordoba
title Comprehensive omic characterization of breast cancer in Mexican-Hispanic women
title_short Comprehensive omic characterization of breast cancer in Mexican-Hispanic women
title_full Comprehensive omic characterization of breast cancer in Mexican-Hispanic women
title_fullStr Comprehensive omic characterization of breast cancer in Mexican-Hispanic women
title_full_unstemmed Comprehensive omic characterization of breast cancer in Mexican-Hispanic women
title_sort comprehensive omic characterization of breast cancer in mexican-hispanic women
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/ee18d53057ea47c8996ebd5a4ca3bc1a
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