Screening participation after a false positive result in organized cervical cancer screening: a nationwide register-based cohort study

Abstract Our aim was to investigate whether receiving a false positive (FP) cervical cytology result affected subsequent cervical cancer screening participation. This Danish nationwide register-based cohort study included 502,380 women aged 22.5–45 attending cervical cancer screening in 2012–2014 wi...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Pernille Thordal Larsen, Susanne Fogh Jørgensen, Mette Tranberg, Sisse Helle Njor
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ee1a1046fbcf4c7599f040981e0334c4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ee1a1046fbcf4c7599f040981e0334c4
record_format	dspace
spelling	oai:doaj.org-article:ee1a1046fbcf4c7599f040981e0334c42021-12-02T18:48:08ZScreening participation after a false positive result in organized cervical cancer screening: a nationwide register-based cohort study10.1038/s41598-020-72279-x2045-2322https://doaj.org/article/ee1a1046fbcf4c7599f040981e0334c42020-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-72279-xhttps://doaj.org/toc/2045-2322Abstract Our aim was to investigate whether receiving a false positive (FP) cervical cytology result affected subsequent cervical cancer screening participation. This Danish nationwide register-based cohort study included 502,380 women aged 22.5–45 attending cervical cancer screening in 2012–2014 with a normal (n = 501,003) or FP (n = 1,377) cytology screening result. A FP result was defined as a cervical cytology showing high grade cytological abnormalities followed by a normal or ‘Cervical Intraepithelial Neoplasia grade 1’ biopsy result. Women were categorized as subsequent participants if they had a cervical cytology within 24–42 months after their last screening or surveillance test. We compared subsequent participation among women with a normal versus a FP result, using odds ratios including 95% confidence intervals. Participation was slightly higher among women with FP results than among women with normal results (71.5% vs. 69.2%, p = 0.058). After adjustment for age and screening history, women with FP results participated significantly more than women with normal results (OR: 1.19, 95% CI 1.06–1.35). Women receiving a FP result did not participate less in subsequent cervical cancer screening than women receiving a normal result. In fact, the use of opportunistic screening seemed to be increased among women receiving a FP result.Pernille Thordal LarsenSusanne Fogh JørgensenMette TranbergSisse Helle NjorNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Pernille Thordal Larsen Susanne Fogh Jørgensen Mette Tranberg Sisse Helle Njor Screening participation after a false positive result in organized cervical cancer screening: a nationwide register-based cohort study
description	Abstract Our aim was to investigate whether receiving a false positive (FP) cervical cytology result affected subsequent cervical cancer screening participation. This Danish nationwide register-based cohort study included 502,380 women aged 22.5–45 attending cervical cancer screening in 2012–2014 with a normal (n = 501,003) or FP (n = 1,377) cytology screening result. A FP result was defined as a cervical cytology showing high grade cytological abnormalities followed by a normal or ‘Cervical Intraepithelial Neoplasia grade 1’ biopsy result. Women were categorized as subsequent participants if they had a cervical cytology within 24–42 months after their last screening or surveillance test. We compared subsequent participation among women with a normal versus a FP result, using odds ratios including 95% confidence intervals. Participation was slightly higher among women with FP results than among women with normal results (71.5% vs. 69.2%, p = 0.058). After adjustment for age and screening history, women with FP results participated significantly more than women with normal results (OR: 1.19, 95% CI 1.06–1.35). Women receiving a FP result did not participate less in subsequent cervical cancer screening than women receiving a normal result. In fact, the use of opportunistic screening seemed to be increased among women receiving a FP result.
format	article
author	Pernille Thordal Larsen Susanne Fogh Jørgensen Mette Tranberg Sisse Helle Njor
author_facet	Pernille Thordal Larsen Susanne Fogh Jørgensen Mette Tranberg Sisse Helle Njor
author_sort	Pernille Thordal Larsen
title	Screening participation after a false positive result in organized cervical cancer screening: a nationwide register-based cohort study
title_short	Screening participation after a false positive result in organized cervical cancer screening: a nationwide register-based cohort study
title_full	Screening participation after a false positive result in organized cervical cancer screening: a nationwide register-based cohort study
title_fullStr	Screening participation after a false positive result in organized cervical cancer screening: a nationwide register-based cohort study
title_full_unstemmed	Screening participation after a false positive result in organized cervical cancer screening: a nationwide register-based cohort study
title_sort	screening participation after a false positive result in organized cervical cancer screening: a nationwide register-based cohort study
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/ee1a1046fbcf4c7599f040981e0334c4
work_keys_str_mv	AT pernillethordallarsen screeningparticipationafterafalsepositiveresultinorganizedcervicalcancerscreeninganationwideregisterbasedcohortstudy AT susannefoghjørgensen screeningparticipationafterafalsepositiveresultinorganizedcervicalcancerscreeninganationwideregisterbasedcohortstudy AT mettetranberg screeningparticipationafterafalsepositiveresultinorganizedcervicalcancerscreeninganationwideregisterbasedcohortstudy AT sissehellenjor screeningparticipationafterafalsepositiveresultinorganizedcervicalcancerscreeninganationwideregisterbasedcohortstudy
_version_	1718377656549900288

Screening participation after a false positive result in organized cervical cancer screening: a nationwide register-based cohort study

Ejemplares similares