Genetic status of KRAS modulates the role of Neuropilin-1 in tumorigenesis

Abstract Neuropilin-1 (NRP1), a non–tyrosine kinase receptor, is overexpressed in many cancers including pancreatic and lung cancers. Inhibition of NRP1 expression, however, has differing pro-tumor vs. anti-tumor effects, depending on the cancer types. To understand the differential role of NRP1 in...

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Bibliographic Details
Main Authors: Sneha Vivekanandhan, Lijuan Yang, Ying Cao, Engfeng Wang, Shamit K. Dutta, Anil K. Sharma, Debabrata Mukhopadhyay
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/ee25eeec42b64df0ac2ab2c256fdf135
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