Inflammatory monocytes promote pre-engraftment syndrome and tocilizumab can therapeutically limit pathology in patients

Pre-engraftment syndrome is a major consideration during clinical application of unrelated cord blood transfusion and monocytes represent a critical cell type in immune-pathogenesis. Here the authors further establish the role of monocytes and GM-CSF in pre-engraftment syndrome and show clinical adm...

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Autores principales:	Linlin Jin, Zimin Sun, Huilan Liu, Xiaoyu Zhu, Yonggang Zhou, Binqing Fu, Xiaohu Zheng, Kaidi Song, Baolin Tang, Yun Wu, Jiang Zhu, Rui Sun, Zhigang Tian, Haiming Wei
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ee31202e507f4a289156fa265f6fb4f4
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spelling	oai:doaj.org-article:ee31202e507f4a289156fa265f6fb4f42021-12-02T15:39:43ZInflammatory monocytes promote pre-engraftment syndrome and tocilizumab can therapeutically limit pathology in patients10.1038/s41467-021-24412-12041-1723https://doaj.org/article/ee31202e507f4a289156fa265f6fb4f42021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24412-1https://doaj.org/toc/2041-1723Pre-engraftment syndrome is a major consideration during clinical application of unrelated cord blood transfusion and monocytes represent a critical cell type in immune-pathogenesis. Here the authors further establish the role of monocytes and GM-CSF in pre-engraftment syndrome and show clinical administration of tocilizumab limits pathology in pre-engraftment syndrome pathology in patients.Linlin JinZimin SunHuilan LiuXiaoyu ZhuYonggang ZhouBinqing FuXiaohu ZhengKaidi SongBaolin TangYun WuJiang ZhuRui SunZhigang TianHaiming WeiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Linlin Jin Zimin Sun Huilan Liu Xiaoyu Zhu Yonggang Zhou Binqing Fu Xiaohu Zheng Kaidi Song Baolin Tang Yun Wu Jiang Zhu Rui Sun Zhigang Tian Haiming Wei Inflammatory monocytes promote pre-engraftment syndrome and tocilizumab can therapeutically limit pathology in patients
description	Pre-engraftment syndrome is a major consideration during clinical application of unrelated cord blood transfusion and monocytes represent a critical cell type in immune-pathogenesis. Here the authors further establish the role of monocytes and GM-CSF in pre-engraftment syndrome and show clinical administration of tocilizumab limits pathology in pre-engraftment syndrome pathology in patients.
format	article
author	Linlin Jin Zimin Sun Huilan Liu Xiaoyu Zhu Yonggang Zhou Binqing Fu Xiaohu Zheng Kaidi Song Baolin Tang Yun Wu Jiang Zhu Rui Sun Zhigang Tian Haiming Wei
author_facet	Linlin Jin Zimin Sun Huilan Liu Xiaoyu Zhu Yonggang Zhou Binqing Fu Xiaohu Zheng Kaidi Song Baolin Tang Yun Wu Jiang Zhu Rui Sun Zhigang Tian Haiming Wei
author_sort	Linlin Jin
title	Inflammatory monocytes promote pre-engraftment syndrome and tocilizumab can therapeutically limit pathology in patients
title_short	Inflammatory monocytes promote pre-engraftment syndrome and tocilizumab can therapeutically limit pathology in patients
title_full	Inflammatory monocytes promote pre-engraftment syndrome and tocilizumab can therapeutically limit pathology in patients
title_fullStr	Inflammatory monocytes promote pre-engraftment syndrome and tocilizumab can therapeutically limit pathology in patients
title_full_unstemmed	Inflammatory monocytes promote pre-engraftment syndrome and tocilizumab can therapeutically limit pathology in patients
title_sort	inflammatory monocytes promote pre-engraftment syndrome and tocilizumab can therapeutically limit pathology in patients
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ee31202e507f4a289156fa265f6fb4f4
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Inflammatory monocytes promote pre-engraftment syndrome and tocilizumab can therapeutically limit pathology in patients

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