Leishmania donovani infection causes distinct epigenetic DNA methylation changes in host macrophages.

Infection of macrophages by the intracellular protozoan Leishmania leads to down-regulation of a number of macrophage innate host defense mechanisms, thereby allowing parasite survival and replication. The underlying molecular mechanisms involved remain largely unknown. In this study, we assessed ep...

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Autores principales: Alexandra K Marr, Julia L MacIsaac, Ruiwei Jiang, Adriana M Airo, Michael S Kobor, W Robert McMaster
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/ee44871f10d64f0ebcca5ebacb35e1bb
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