The Deleterious Effects of Shiga Toxin Type 2 Are Neutralized In Vitro by FabF8:Stx2 Recombinant Monoclonal Antibody

The Deleterious Effects of Shiga Toxin Type 2 Are Neutralized In Vitro by FabF8:Stx2 Recombinant Monoclonal Antibody

Hemolytic Uremic Syndrome (HUS) associated with Shiga-toxigenic <i>Escherichia coli</i> (STEC) infections is the principal cause of acute renal injury in pediatric age groups. Shiga toxin type 2 (Stx2) has in vitro cytotoxic effects on kidney cells, including human glomerular endothelial...

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Auteurs principaux: Daniela Luz, Fernando D. Gómez, Raíssa L. Ferreira, Bruna S. Melo, Beatriz E. C. Guth, Wagner Quintilio, Ana Maria Moro, Agostina Presta, Flavia Sacerdoti, Cristina Ibarra, Gang Chen, Sachdev S. Sidhu, María Marta Amaral, Roxane M. F. Piazza
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
STEC
Stx2
antibody fragment
monoclonal antibody
Medicine
R
Accès en ligne:https://doaj.org/article/ee4e3434a60a4688a020358caa726ff9
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