RuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution

Holliday junctions (HJs) are four-way DNA structures that occur in DNA repair by homologous recombination which are removed by nucleases such as RuvC. Here the authors provide structural and biochemical details on the steps required for the completion of the process.

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Autores principales:	Karolina Maria Górecka, Miroslav Krepl, Aleksandra Szlachcic, Jarosław Poznański, Jiří Šponer, Marcin Nowotny
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ee4f387405724f7facf85dd79c1e37a1
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spelling	oai:doaj.org-article:ee4f387405724f7facf85dd79c1e37a12021-12-02T16:58:15ZRuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution10.1038/s41467-019-11900-82041-1723https://doaj.org/article/ee4f387405724f7facf85dd79c1e37a12019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11900-8https://doaj.org/toc/2041-1723Holliday junctions (HJs) are four-way DNA structures that occur in DNA repair by homologous recombination which are removed by nucleases such as RuvC. Here the authors provide structural and biochemical details on the steps required for the completion of the process.Karolina Maria GóreckaMiroslav KreplAleksandra SzlachcicJarosław PoznańskiJiří ŠponerMarcin NowotnyNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Karolina Maria Górecka Miroslav Krepl Aleksandra Szlachcic Jarosław Poznański Jiří Šponer Marcin Nowotny RuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution
description	Holliday junctions (HJs) are four-way DNA structures that occur in DNA repair by homologous recombination which are removed by nucleases such as RuvC. Here the authors provide structural and biochemical details on the steps required for the completion of the process.
format	article
author	Karolina Maria Górecka Miroslav Krepl Aleksandra Szlachcic Jarosław Poznański Jiří Šponer Marcin Nowotny
author_facet	Karolina Maria Górecka Miroslav Krepl Aleksandra Szlachcic Jarosław Poznański Jiří Šponer Marcin Nowotny
author_sort	Karolina Maria Górecka
title	RuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution
title_short	RuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution
title_full	RuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution
title_fullStr	RuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution
title_full_unstemmed	RuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution
title_sort	ruvc uses dynamic probing of the holliday junction to achieve sequence specificity and efficient resolution
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/ee4f387405724f7facf85dd79c1e37a1
work_keys_str_mv	AT karolinamariagorecka ruvcusesdynamicprobingofthehollidayjunctiontoachievesequencespecificityandefficientresolution AT miroslavkrepl ruvcusesdynamicprobingofthehollidayjunctiontoachievesequencespecificityandefficientresolution AT aleksandraszlachcic ruvcusesdynamicprobingofthehollidayjunctiontoachievesequencespecificityandefficientresolution AT jarosławpoznanski ruvcusesdynamicprobingofthehollidayjunctiontoachievesequencespecificityandefficientresolution AT jirisponer ruvcusesdynamicprobingofthehollidayjunctiontoachievesequencespecificityandefficientresolution AT marcinnowotny ruvcusesdynamicprobingofthehollidayjunctiontoachievesequencespecificityandefficientresolution
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RuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution

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