Retinoic acid signaling drives differentiation toward the absorptive lineage in colorectal cancer

Summary: Retinoic acid (RA) signaling is an important and conserved pathway that regulates cellular proliferation and differentiation. Furthermore, perturbed RA signaling is implicated in cancer initiation and progression. However, the mechanisms by which RA signaling contributes to homeostasis, mal...

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Main Authors: Roelof A. Wester, Lisa van Voorthuijsen, Hannah K. Neikes, Jelmer J. Dijkstra, Lieke A. Lamers, Siebren Frölich, Maarten van der Sande, Colin Logie, Rik G.H. Lindeboom, Michiel Vermeulen
Format: article
Language:EN
Published: Elsevier 2021
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Online Access:https://doaj.org/article/ee53bbefaa5245eea4b658c2b77ce466
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