FLOW CYTOMETRY AS A MODERN ANALYTICAL TOOL IN BIOLOGY AND MEDICINE

Abstract. Flow cytometry is considered as a modern technology for fast measurements of cellular characteristics, their organelles, and processes occurring within them. It is regarded as an efficient solution in many important areas of cell biology, immunology and cellular engineering. Present articl...

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Autores principales: S. V. Khaidukov, A. V. Zurochka
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Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/ee596e5677b64fdba6ede68b97224ded
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spelling oai:doaj.org-article:ee596e5677b64fdba6ede68b97224ded2021-11-18T08:03:38ZFLOW CYTOMETRY AS A MODERN ANALYTICAL TOOL IN BIOLOGY AND MEDICINE1563-06252313-741X10.15789/1563-0625-2007-4-5-https://doaj.org/article/ee596e5677b64fdba6ede68b97224ded2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/176https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Flow cytometry is considered as a modern technology for fast measurements of cellular characteristics, their organelles, and processes occurring within them. It is regarded as an efficient solution in many important areas of cell biology, immunology and cellular engineering. Present article bears on main developments in flow cytometry and their applications in medical and biological practice. Usage of modern achievements in fluorescent dyes, progress in laser and computer technologies, as well as potent software, resulted in wide application of this technique in medical practice. Accordingly, usage of monoclonal antibodies conjugated to different fluorochromes has led to elaboration of multiparametric analysis and did sufficiently simplify specialized works aimed for diagnostics of various immune disorders. The new directions in flow cytometry, e.g., flow cytoenzymology, provide wide opportunities for detailed identification of damaged or altered cells, and taking adequate decisions in treatment of detected pathological changes. The authors suggest that this article could initiate a series of publications concerning usage of this technology and its modern applications in broad laboratory practice.S. V. KhaidukovA. V. ZurochkaSPb RAACIarticleflow cytometrycell sortingmultiparametric analysisof monoclonal antibodiesfluorochromesImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 9, Iss 4-5, Pp 373-378 (2014)
institution DOAJ
collection DOAJ
language RU
topic flow cytometry
cell sorting
multiparametric analysis
of monoclonal antibodies
fluorochromes
Immunologic diseases. Allergy
RC581-607
spellingShingle flow cytometry
cell sorting
multiparametric analysis
of monoclonal antibodies
fluorochromes
Immunologic diseases. Allergy
RC581-607
S. V. Khaidukov
A. V. Zurochka
FLOW CYTOMETRY AS A MODERN ANALYTICAL TOOL IN BIOLOGY AND MEDICINE
description Abstract. Flow cytometry is considered as a modern technology for fast measurements of cellular characteristics, their organelles, and processes occurring within them. It is regarded as an efficient solution in many important areas of cell biology, immunology and cellular engineering. Present article bears on main developments in flow cytometry and their applications in medical and biological practice. Usage of modern achievements in fluorescent dyes, progress in laser and computer technologies, as well as potent software, resulted in wide application of this technique in medical practice. Accordingly, usage of monoclonal antibodies conjugated to different fluorochromes has led to elaboration of multiparametric analysis and did sufficiently simplify specialized works aimed for diagnostics of various immune disorders. The new directions in flow cytometry, e.g., flow cytoenzymology, provide wide opportunities for detailed identification of damaged or altered cells, and taking adequate decisions in treatment of detected pathological changes. The authors suggest that this article could initiate a series of publications concerning usage of this technology and its modern applications in broad laboratory practice.
format article
author S. V. Khaidukov
A. V. Zurochka
author_facet S. V. Khaidukov
A. V. Zurochka
author_sort S. V. Khaidukov
title FLOW CYTOMETRY AS A MODERN ANALYTICAL TOOL IN BIOLOGY AND MEDICINE
title_short FLOW CYTOMETRY AS A MODERN ANALYTICAL TOOL IN BIOLOGY AND MEDICINE
title_full FLOW CYTOMETRY AS A MODERN ANALYTICAL TOOL IN BIOLOGY AND MEDICINE
title_fullStr FLOW CYTOMETRY AS A MODERN ANALYTICAL TOOL IN BIOLOGY AND MEDICINE
title_full_unstemmed FLOW CYTOMETRY AS A MODERN ANALYTICAL TOOL IN BIOLOGY AND MEDICINE
title_sort flow cytometry as a modern analytical tool in biology and medicine
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/ee596e5677b64fdba6ede68b97224ded
work_keys_str_mv AT svkhaidukov flowcytometryasamodernanalyticaltoolinbiologyandmedicine
AT avzurochka flowcytometryasamodernanalyticaltoolinbiologyandmedicine
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