Impact of chronic obstructive pulmonary diseases on left ventricular diastolic function in hospitalized elderly patients

Impact of chronic obstructive pulmonary diseases on left ventricular diastolic function in hospitalized elderly patients

Ying-Shuo Huang, Ying-Chao Feng, Jian Zhang, Li Bai, Wei Huang, Min Li, Ying Sun Department of Geriatrics and Gerontology, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China Objective: To evaluate the impact of chronic obstructive pulmonary diseas...

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Autores principales: Huang YS, Feng YC, Zhang J, Bai L, Huang W, Li M, Sun Y
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2014
Materias:
Key Words: Chronic obstructive pulmonary disease
Heart failure
Left ventricular diastolic dysfunction
Elderly
Echocardiography
Geriatrics
RC952-954.6
Acceso en línea:https://doaj.org/article/ee59bdfee1dd4786bd8681e2befb6614
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spelling oai:doaj.org-article:ee59bdfee1dd4786bd8681e2befb66142021-12-02T05:51:39ZImpact of chronic obstructive pulmonary diseases on left ventricular diastolic function in hospitalized elderly patients1178-1998https://doaj.org/article/ee59bdfee1dd4786bd8681e2befb66142014-12-01T00:00:00Zhttps://www.dovepress.com/impact-of-chronic-obstructive-pulmonary-diseases-on-left-ventricular-d-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Ying-Shuo Huang, Ying-Chao Feng, Jian Zhang, Li Bai, Wei Huang, Min Li, Ying Sun Department of Geriatrics and Gerontology, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China Objective: To evaluate the impact of chronic obstructive pulmonary disease (COPD) on left ventricular (LV) diastolic function in hospitalized elderly patients.Methods: This was a case–control observational study of 148 consecutive hospitalized elderly patients (≥65 years old): 73 subjects without COPD as controls and 75 patients with COPD. Mild-to-moderate COPD was defined as stages 1 and 2, while severe and very severe COPD was defined as stages 3 and 4, according to the Global Initiative for Chronic Obstructive Lung Disease guidelines. Clinical characteristics and echocardiographic parameters were analyzed and compared.Results: Compared with the control group, patients with COPD had a higher frequency of LV diastolic dysfunction and heart failure with preserved ejection fraction. Smoking frequency, frequency of cerebrovascular diseases and diabetes, and serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels were higher in the COPD group (all P<0.05). COPD patients showed more abnormalities in diastolic function (E/e': 11.51±2.50 vs 10.42±3.25, P=0.047), but no differences in systolic function and right ventricular function (all P>0.05). Patients with severe/very severe COPD showed no differences in LV diastolic function compared to patients with mild/moderate COPD (P>0.05), but serum NT-proBNP levels were higher in severe/very severe COPD (P<0.05).Conclusion: Results suggest that early-stage COPD may have an impact on the LV diastolic function. Severe COPD mainly affected right ventricular function. In hospitalized elderly patients with COPD, LV diastolic dysfunction should be taken into account together with right ventricular function. Keywords: chronic obstructive pulmonary disease, heart failure, left ventricular diastolic dysfunction, elderly, echocardiographyHuang YSFeng YCZhang JBai LHuang WLi MSun YDove Medical PressarticleKey Words: Chronic obstructive pulmonary diseaseHeart failureLeft ventricular diastolic dysfunctionElderlyEchocardiographyGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 10, Pp 81-87 (2014)
institution DOAJ
collection DOAJ
language EN
topic Key Words: Chronic obstructive pulmonary disease
Heart failure
Left ventricular diastolic dysfunction
Elderly
Echocardiography
Geriatrics
RC952-954.6
spellingShingle Key Words: Chronic obstructive pulmonary disease
Heart failure
Left ventricular diastolic dysfunction
Elderly
Echocardiography
Geriatrics
RC952-954.6
Huang YS
Feng YC
Zhang J
Bai L
Huang W
Li M
Sun Y
Impact of chronic obstructive pulmonary diseases on left ventricular diastolic function in hospitalized elderly patients
description Ying-Shuo Huang, Ying-Chao Feng, Jian Zhang, Li Bai, Wei Huang, Min Li, Ying Sun Department of Geriatrics and Gerontology, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China Objective: To evaluate the impact of chronic obstructive pulmonary disease (COPD) on left ventricular (LV) diastolic function in hospitalized elderly patients.Methods: This was a case–control observational study of 148 consecutive hospitalized elderly patients (≥65 years old): 73 subjects without COPD as controls and 75 patients with COPD. Mild-to-moderate COPD was defined as stages 1 and 2, while severe and very severe COPD was defined as stages 3 and 4, according to the Global Initiative for Chronic Obstructive Lung Disease guidelines. Clinical characteristics and echocardiographic parameters were analyzed and compared.Results: Compared with the control group, patients with COPD had a higher frequency of LV diastolic dysfunction and heart failure with preserved ejection fraction. Smoking frequency, frequency of cerebrovascular diseases and diabetes, and serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels were higher in the COPD group (all P<0.05). COPD patients showed more abnormalities in diastolic function (E/e': 11.51±2.50 vs 10.42±3.25, P=0.047), but no differences in systolic function and right ventricular function (all P>0.05). Patients with severe/very severe COPD showed no differences in LV diastolic function compared to patients with mild/moderate COPD (P>0.05), but serum NT-proBNP levels were higher in severe/very severe COPD (P<0.05).Conclusion: Results suggest that early-stage COPD may have an impact on the LV diastolic function. Severe COPD mainly affected right ventricular function. In hospitalized elderly patients with COPD, LV diastolic dysfunction should be taken into account together with right ventricular function. Keywords: chronic obstructive pulmonary disease, heart failure, left ventricular diastolic dysfunction, elderly, echocardiography
format article
author Huang YS
Feng YC
Zhang J
Bai L
Huang W
Li M
Sun Y
author_facet Huang YS
Feng YC
Zhang J
Bai L
Huang W
Li M
Sun Y
author_sort Huang YS
title Impact of chronic obstructive pulmonary diseases on left ventricular diastolic function in hospitalized elderly patients
title_short Impact of chronic obstructive pulmonary diseases on left ventricular diastolic function in hospitalized elderly patients
title_full Impact of chronic obstructive pulmonary diseases on left ventricular diastolic function in hospitalized elderly patients
title_fullStr Impact of chronic obstructive pulmonary diseases on left ventricular diastolic function in hospitalized elderly patients
title_full_unstemmed Impact of chronic obstructive pulmonary diseases on left ventricular diastolic function in hospitalized elderly patients
title_sort impact of chronic obstructive pulmonary diseases on left ventricular diastolic function in hospitalized elderly patients
publisher Dove Medical Press
publishDate 2014
url https://doaj.org/article/ee59bdfee1dd4786bd8681e2befb6614
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