Inhibition of GTPase Rac1 expression by vitamin D mitigates pressure overload-induced cardiac hypertrophy
Background: 1, 25-dihydroxy Vitamin D3 (VitD) attenuates left ventricular hypertrophy (LVH), but the mechanisms remain to be portrayed in-depth. The small GTPase Rac1 plays a pivotal role in cardiovascular pathology, especially LVH. Here, we tested whether VitD exerts its anti-LVH effects by counter...
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Main Authors: | Ali Moradi, Abdulbaset Maroofi, Mahdie Hemati, Tahmine Hashemzade, Nasrin Alborzi, Fatemeh Safari |
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Format: | article |
Language: | EN |
Published: |
Elsevier
2021
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Online Access: | https://doaj.org/article/ee59d877f64a4c8fbe7f0976c8b03b6a |
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