Inhibition of GTPase Rac1 expression by vitamin D mitigates pressure overload-induced cardiac hypertrophy

Background: 1, 25-dihydroxy Vitamin D3 (VitD) attenuates left ventricular hypertrophy (LVH), but the mechanisms remain to be portrayed in-depth. The small GTPase Rac1 plays a pivotal role in cardiovascular pathology, especially LVH. Here, we tested whether VitD exerts its anti-LVH effects by counter...

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Auteurs principaux: Ali Moradi, Abdulbaset Maroofi, Mahdie Hemati, Tahmine Hashemzade, Nasrin Alborzi, Fatemeh Safari
Format: article
Langue:EN
Publié: Elsevier 2021
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Accès en ligne:https://doaj.org/article/ee59d877f64a4c8fbe7f0976c8b03b6a
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