High IL-17E and low IL-17C dermal expression identifies a fibrosis-specific motif common to morphea and systemic sclerosis.

High IL-17E and low IL-17C dermal expression identifies a fibrosis-specific motif common to morphea and systemic sclerosis.

<h4>Background</h4>High interleukin (IL)-17A levels are characteristically found in the skin of systemic sclerosis (SSc) individuals. Our aim was to investigate whether the dermal expression of IL-17A and related IL-17 family members (i.e. IL-17C, IL-17E and IL-17F) could distinguish fib...

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Main Authors: Paola Adele Lonati, Nicolò Costantino Brembilla, Elisa Montanari, Lionel Fontao, Armando Gabrielli, Serena Vettori, Gabriele Valentini, Emmanuel Laffitte, Gurkan Kaya, Pier-Luigi Meroni, Carlo Chizzolini
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/ee5ef60630d9491990049ddf0472b645
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